PLA2G6 anticorps (AA 651-750) (Alexa Fluor 594)

N° du produit ABIN2811033

Détail du produit anti-PLA2G6 anticorps (Alexa Fluor 594)

Antigène: PLA2G6 (Phospholipase A2, Group VI (Cytosolic, Calcium-Independent) (PLA2G6))

Épitope: AA 651-750

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLA2G6 est conjugé à/à la Alexa Fluor 594

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Rat

Homologie: Human,Mouse,Dog,Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human CaI-PLA2/PLA2G6

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur PLA2G6

Antigène: PLA2G6 (Phospholipase A2, Group VI (Cytosolic, Calcium-Independent) (PLA2G6))

Autre désignation: CaI-PLA2 (PLA2G6 Produits)

Synonymes: anticorps zgc:77476, anticorps wu:fc06g09, anticorps PNPLA9, anticorps MGC83523, anticorps PLA2G6, anticorps BB112799, anticorps iPLA(2)beta, anticorps iPLA2, anticorps iPLA2beta, anticorps CaI-PLA2, anticorps GVI, anticorps INAD1, anticorps IPLA2-VIA, anticorps NBIA2, anticorps NBIA2A, anticorps NBIA2B, anticorps PARK14, anticorps PLA2, anticorps iPla2, anticorps phospholipase A2, group VI (cytosolic, calcium-independent), anticorps phospholipase A2 group VI, anticorps phospholipase A2 group VI S homeolog, anticorps 85/88 kDa calcium-independent phospholipase A2, anticorps phospholipase A2, group VI, anticorps pla2g6, anticorps PLA2G6, anticorps pla2g6.S, anticorps LOC100445065, anticorps Pla2g6

Sujet:

Synonyms: GVI, PLA2, INAD1, NBIA2, iPLA2, NBIA2A, NBIA2B, PARK14, PNPLA9, CaI-PLA2, IPLA2-VIA, iPLA2beta, 85/88 kDa calcium-independent phospholipase A2, Group VI phospholipase A2, GVI PLA2, Intracellular membrane-associated calcium-independent phospholipase A2 beta, iPLA2-beta, Patatin-like phospholipase domain-containing protein 9, PLA2G6, PLPLA9

Background: Catalyzes the release of fatty acids from phospholipids. It has been implicated in normal phospholipid remodeling, nitric oxide-induced or vasopressin-induced arachidonic acid release and in leukotriene and prostaglandin production. May participate in fas mediated apoptosis and in regulating transmembrane ion flux in glucose-stimulated B-cells. Has a role in cardiolipin (CL) deacylation. Required for both speed and directionality of monocyte MCP1/CCL2-induced chemotaxis through regulation of F-actin polymerization at the pseudopods. Isoform ankyrin-iPLA2-1 and isoform ankyrin-iPLA2-2, which lack the catalytic domain, are probably involved in the negative regulation of iPLA2 activity.

ID gène: 8398

UniProt: O60733

Pathways: Positive Regulation of Peptide Hormone Secretion