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CCDC98 anticorps (AA 51-150) (Alexa Fluor 594)

FAM175A Reactivité: Souris WB, IF (cc), IF (p) Hôte: Lapin Polyclonal Alexa Fluor 594
N° du produit ABIN2811242
  • Antigène Voir toutes CCDC98 (FAM175A) Anticorps
    CCDC98 (FAM175A) (Family with Sequence Similarity 175, Member A (FAM175A))
    Épitope
    • 14
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    AA 51-150
    Reactivité
    • 26
    • 18
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Souris
    Hôte
    • 37
    • 4
    Lapin
    Clonalité
    • 36
    • 5
    Polyclonal
    Conjugué
    • 19
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CCDC98 est conjugé à/à la Alexa Fluor 594
    Application
    • 32
    • 14
    • 12
    • 12
    • 11
    • 9
    • 6
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Souris
    Homologie
    Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human CCDC98
    Isotype
    IgG
    Top Product
    Discover our top product FAM175A Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    CCDC98 (FAM175A) (Family with Sequence Similarity 175, Member A (FAM175A))
    Autre désignation
    CCDC98 (FAM175A Produits)
    Synonymes
    anticorps CCDC98, anticorps abra1, anticorps ccdc98, anticorps fam175a, anticorps ABRA1, anticorps 3830405G04Rik, anticorps 5630400M01Rik, anticorps AI506069, anticorps AL024423, anticorps AV118690, anticorps Ccdc98, anticorps RGD1305287, anticorps zgc:103522, anticorps abraxas 1, BRCA1 A complex subunit, anticorps Coiled-coil domain-containing protein 98, anticorps BRCA1 A complex subunit, anticorps family with sequence similarity 175 member A, anticorps abraxas 2a, BRISC complex subunit, anticorps abraxas 1, BRCA1 A complex subunit S homeolog, anticorps ABRAXAS1, anticorps abraxas1, anticorps Abraxas1, anticorps FAM175A, anticorps abraxas2a, anticorps abraxas1.S
    Sujet

    Synonyms: ABRA1, CCDC98, BRCA1-A complex subunit Abraxas, Coiled-coil domain-containing protein 98, Protein FAM175A, FAM175A, UNQ496/PRO1013

    Background: Involved in DNA damage response and double-strand break (DSB) repair. Component of the BRCA1-A complex, acting as a central scaffold protein that assembles the various components of the complex and mediates the recruitment of BRCA1. The BRCA1-A complex specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesion sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at DSBs. This complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX.

    ID gène
    84142
    UniProt
    Q6UWZ7
    Pathways
    Réparation de l'ADN, Positive Regulation of Response to DNA Damage Stimulus
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