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RPRD1B anticorps (Alexa Fluor 594)

RPRD1B Reactivité: Humain, Souris, Rat WB, IF (p) Hôte: Lapin Polyclonal Alexa Fluor 594
N° du produit ABIN2811927
  • Antigène Voir toutes RPRD1B Anticorps
    RPRD1B (Regulation of Nuclear Pre-mRNA Domain Containing 1B (RPRD1B))
    Reactivité
    • 44
    • 20
    • 19
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Humain, Souris, Rat
    Hôte
    • 41
    • 3
    Lapin
    Clonalité
    • 41
    • 3
    Polyclonal
    Conjugué
    • 17
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp RPRD1B est conjugé à/à la Alexa Fluor 594
    Application
    • 40
    • 18
    • 14
    • 12
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Humain, Souris, Rat
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human CREPT
    Isotype
    IgG
    Top Product
    Discover our top product RPRD1B Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    RPRD1B (Regulation of Nuclear Pre-mRNA Domain Containing 1B (RPRD1B))
    Autre désignation
    CREPT (RPRD1B Produits)
    Synonymes
    anticorps fb23h08, anticorps zgc:55687, anticorps wu:fb23h08, anticorps rprd1ba, anticorps MGC130705, anticorps C13H20ORF77, anticorps C20orf77, anticorps CREPT, anticorps NET60, anticorps dJ1057B20.2, anticorps 2610304G08Rik, anticorps 2810446G03Rik, anticorps Crept, anticorps RGD1304782, anticorps regulation of nuclear pre-mRNA domain containing 1B, anticorps regulation of nuclear pre-mRNA domain containing 1B L homeolog, anticorps rprd1b, anticorps rprd1b.L, anticorps RPRD1B, anticorps Rprd1b
    Sujet

    Synonyms: C20orf77, Cell cycle related and expression elevated protein in tumor, Chromosome 20 open reading frame 77, CREPT, dJ1057B20.2, DKFZp434P0735, FLJ44520, Hypothetical protein LOC58490, Uncharacterized protein C20orf77, RPR1B_HUMAN.

    Background: Interacts with phosphorylated C-terminal heptapeptiderepeat domain (CTD) of the largest RNA polymerase II subunitPOLR2A, and participates in dephosphorylation of the CTD.Transcriptional regulator which enhances expression of CCND1.Promotes binding of RNA polymerase II to the CCDN1 promoter and tothe termination region before the poly-A site but decreases itsbinding after the poly-A site. Prevents RNA polymerase II fromreading through the 3' end termination site and may allow it to berecruited back to the promoter through promotion of the formationof a chromatin loop. Also enhances the transcription of a number ofother cell cycle-related genes including CDK2, CDK4, CDK6 andcyclin-E but not CDKN1A, CDKN1B or cyclin-A. Promotes cell proliferation.

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