GLI4 anticorps (AA 271-376) (Alexa Fluor 594)

N° du produit ABIN2813771

Détail du produit anti-GLI4 anticorps (Alexa Fluor 594)

Antigène: GLI4 (GLI Family Zinc Finger Protein 4 (GLI4))

Épitope: AA 271-376

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GLI4 est conjugé à/à la Alexa Fluor 594

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Humain

Homologie: Mouse,Rat,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human GLI4

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur GLI4

Antigène: GLI4 (GLI Family Zinc Finger Protein 4 (GLI4))

Autre désignation: GLI4 (GLI4 Produits)

Synonymes: anticorps HKR4, anticorps ZNF928, anticorps GLI4, anticorps GLI family zinc finger 4, anticorps RIKEN cDNA 9130023H24 gene, anticorps GLI4, anticorps 9130023H24Rik, anticorps Gli4

Sujet:

Synonyms: GLI 4, GLI Kruppel family member GLI 4, GLI Kruppel family member GLI4, GLI4, GLI4_HUMAN, HKR 4, HKR4, HKR4 protein, Krueppel related zinc finger protein 4, Krueppel-related zinc finger protein 4, Neural specic DNA binding protein, Oncogene HKR 4, Oncogene HKR4, Protein HKR 4, Protein HKR4, Zinc finger protein GLI 4, Zinc finger protein GLI4.

Background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a krueppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. GLI-4, also known as HKR4, is a 376 amino acid protein that localizes to the nucleus and contains seven C2H2-type zinc fingers. Belonging to the krueppel C2H2-type zinc-finger protein family, GLI-4 may function as a transcriptional regulator, effectively activating or repressing the transcription of target genes. The gene encoding GLI-4 maps to human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies.

ID gène: 2738