HBV PreS1,PreS2 anticorps (Alexa Fluor 594)

N° du produit ABIN2814166

Détail du produit anti-HBV PreS1,PreS2 anticorps (Alexa Fluor 594)

Antigène: HBV PreS1,PreS2 (Hepatitis B Virus PreS1/PreS2 Protein (HBV PreS1,PreS2))

Reactivité: Virus

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HBV PreS1,PreS2 est conjugé à/à la Alexa Fluor 594

Application: Western Blotting (WB)

Réactivité croisée: Virus

Réactivité croisée (Details): Hepatitis B virus ay/ad

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from HBSAG_HBVD2 sub. ayw pre S1/S2 protein

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur HBV PreS1,PreS2

Antigène: HBV PreS1,PreS2 (Hepatitis B Virus PreS1/PreS2 Protein (HBV PreS1,PreS2))

Autre désignation: HBV Pre S1/ S2 Protein (HBV PreS1,PreS2 Produits)

Classe de substances: Viral Protein

Sujet:

Synonyms: Hepatitis B, HBSAG_HBVD2, HBSAG_HBVC5, Large envelope protein, Large surface protein, L glycoprotein, Major surface antigen, Large S protein, L-HBsAg, LHB

Background: Hepatitis B Virus (HBV) infection induces a disease state characterised by liver damage, inflammation and viral persistence. Infection also increases the risk of hepatocellular carcinoma. HBV belongs to the Hepadnaviridae family of viruses. Its genome consists of partially double stranded circular DNA. The DNA is enclosed in a nucleocapsid, or core antigen (HBcAg), which is surrounded by a spherical envelope (surface antigen or HBsAg). The core antigen shares its sequences with the e antigen (HBeAg) but no cross reactivity between the two proteins has been observed. The HBV genome also encodes a DNA polymerase that also acts as a reverse transcriptase. Hepatitis B infection is normally diagnosed from serological tests that detect HBsAg but as the disease progresses this antigen may no longer be present in the blood and tests for HBcAg are used. If HBsAg can be detected in the blood for longer than six months, chronic hepatitis B is diagnosed. The antigenic determinant of the protein moiety of the HBsAg determines specific characteristics of different serotypes and provides the basis of immunodetection. HBsAg has antigenic heterogeneity, specifically, two pairs of sub specific determinants, d/y and w/r allow the following combinations: adw, ayw, adr, ayr.