Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

KIT anticorps (pSer891)

KIT Reactivité: Humain DB Hôte: Lapin Polyclonal RB41777 unconjugated
N° du produit ABIN2850471
  • Antigène Voir toutes KIT Anticorps
    KIT (Mast/stem Cell Growth Factor Receptor (KIT))
    Épitope
    • 55
    • 55
    • 35
    • 28
    • 23
    • 23
    • 23
    • 21
    • 16
    • 16
    • 16
    • 16
    • 16
    • 16
    • 16
    • 14
    • 13
    • 13
    • 12
    • 12
    • 10
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 6
    pSer891
    Reactivité
    • 675
    • 241
    • 66
    • 29
    • 28
    • 28
    • 17
    • 13
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    Humain
    Hôte
    • 602
    • 107
    • 48
    • 2
    • 1
    Lapin
    Clonalité
    • 594
    • 166
    • 1
    Polyclonal
    Conjugué
    • 231
    • 81
    • 78
    • 77
    • 62
    • 60
    • 14
    • 14
    • 13
    • 13
    • 13
    • 13
    • 11
    • 10
    • 10
    • 10
    • 10
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp KIT est non-conjugé
    Application
    • 432
    • 394
    • 299
    • 147
    • 91
    • 91
    • 68
    • 50
    • 46
    • 46
    • 34
    • 25
    • 10
    • 6
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dot Blot (DB)
    Homologie
    B, Pig
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This KIT Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S891 of human KIT.
    Clone
    RB41777
    Isotype
    Ig Fraction
    Top Product
    Discover our top product KIT Anticorps primaire
  • Indications d'application
    DB: 1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Date de péremption
    6 months
  • Molderings, Meis, Kolck, Homann, Frieling: "Comparative analysis of mutation of tyrosine kinase kit in mast cells from patients with systemic mast cell activation syndrome and healthy subjects." dans: Immunogenetics, Vol. 62, Issue 11-12, pp. 721-7, (2010) (PubMed).

    Cheng, Zhou, Wu, Boriboun, Thorne, Liu, Xiang, Zeng, Tanaka, Tang, Kishore, Tomasson, Miller, Losordo, Qin: "CXCR4-mediated bone marrow progenitor cell maintenance and mobilization are modulated by c-kit activity." dans: Circulation research, Vol. 107, Issue 9, pp. 1083-93, (2010) (PubMed).

    Chi, Chen, Zhang, Guo, Wongvipat, Shamu, Fletcher, Dewell, Maki, Zheng, Antonescu, Allis, Sawyers: "ETV1 is a lineage survival factor that cooperates with KIT in gastrointestinal stromal tumours." dans: Nature, Vol. 467, Issue 7317, pp. 849-53, (2010) (PubMed).

    Rossi, Gasparotto, Toffolatti, Pastrello, Gallina, Marzotto, Sartor, Barbareschi, Cantaloni, Messerini, Bearzi, Arrigoni, Mazzoleni, Fletcher, Casali, Talamini, Maestro, Maestra, Dei Tos: "Molecular and clinicopathologic characterization of gastrointestinal stromal tumors (GISTs) of small size." dans: The American journal of surgical pathology, Vol. 34, Issue 10, pp. 1480-91, (2010) (PubMed).

    Chen, Zong, Zhao, Shi: "Efficacy evaluation of imatinib treatment in patients with gastrointestinal stromal tumors: a meta-analysis." dans: World journal of gastroenterology : WJG, Vol. 16, Issue 33, pp. 4227-32, (2010) (PubMed).

  • Antigène
    KIT (Mast/stem Cell Growth Factor Receptor (KIT))
    Autre désignation
    KIT (KIT Produits)
    Synonymes
    anticorps C-Kit, anticorps CD117, anticorps PBT, anticorps SCFR, anticorps Bs, anticorps Fdc, anticorps Gsfsco1, anticorps Gsfsco5, anticorps Gsfsow3, anticorps SCO1, anticorps SCO5, anticorps SOW3, anticorps Ssm, anticorps Tr-kit, anticorps W, anticorps c-KIT, anticorps c-kit, anticorps MGF, anticorps KIT, anticorps C-KIT, anticorps kit, anticorps receptor, anticorps sparse, anticorps Xkl-1, anticorps kit-a, anticorps kit-b, anticorps kl1-A, anticorps krk1, anticorps pbt, anticorps scfr, anticorps KIT proto-oncogene receptor tyrosine kinase, anticorps v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog a, anticorps KIT proto-oncogene receptor tyrosine kinase S homeolog, anticorps KIT, anticorps Kit, anticorps kita, anticorps kit, anticorps kit.S
    Sujet
    This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.
    Poids moléculaire
    109865
    NCBI Accession
    NP_000213, NP_001087241
    UniProt
    P10721
    Pathways
    Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity
Vous êtes ici:
Support technique