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PKC epsilon anticorps

PRKCE Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2854518
  • Antigène Voir toutes PKC epsilon (PRKCE) Anticorps
    PKC epsilon (PRKCE) (Protein Kinase C, epsilon (PRKCE))
    Reactivité
    • 91
    • 68
    • 55
    • 6
    • 4
    • 2
    • 1
    Humain
    Hôte
    • 119
    • 7
    • 1
    Lapin
    Clonalité
    • 111
    • 16
    Polyclonal
    Conjugué
    • 52
    • 13
    • 8
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp PKC epsilon est non-conjugé
    Application
    • 101
    • 52
    • 29
    • 28
    • 28
    • 16
    • 9
    • 9
    • 8
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB)
     Réactivité croisée
    Humain
    Attributs du produit
    Rabbit Polyclonal antibody to PKC epsilon (protein kinase C, epsilon)
    PKC epsilon antibody [N2C2], Internal
    Purification
    Purified by antigen-affinity chromatography.
    Immunogène
    Recombinant protein encompassing a sequence within the center region of human PKC epsilon. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product PRKCE Anticorps primaire
  • Indications d'application
    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Commentaires

    Positive Control: A431

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.92 mg/mL
    Buffer
    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
    Agent conservateur
    Thimerosal (Merthiolate)
    Précaution d'utilisation
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Antigène
    PKC epsilon (PRKCE) (Protein Kinase C, epsilon (PRKCE))
    Autre désignation
    protein kinase C epsilon (PRKCE Produits)
    Synonymes
    anticorps PKCE, anticorps nPKC-epsilon, anticorps 5830406C15Rik, anticorps PKC[e], anticorps PKCepsilon, anticorps Pkce, anticorps R75156, anticorps fj59b07, anticorps prkce, anticorps wu:fj59b07, anticorps pkce, anticorps pkc-epsilon, anticorps PRKCH, anticorps protein kinase C epsilon, anticorps protein kinase C, epsilon, anticorps protein kinase C, epsilon a, anticorps PRKCE, anticorps Prkce, anticorps prkcea, anticorps prkce
    Sujet
    Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been shown to be involved in many different cellular functions, such as neuron channel activation, apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior.

    Poids moléculaire
    84 kDa
    ID gène
    5581
    UniProt
    Q02156
    Pathways
    TCR Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Myometrial Relaxation and Contraction, Regulation of Carbohydrate Metabolic Process, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling
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