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GALR2 anticorps (C-Term)

GALR2 Reactivité: Humain WB, IHC (p), IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2854711
  • Antigène Voir toutes GALR2 Anticorps
    GALR2 (Galanin Receptor 2 (GALR2))
    Épitope
    • 16
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 38
    • 27
    • 25
    • 5
    • 4
    • 4
    • 1
    Humain
    Hôte
    • 38
    • 1
    Lapin
    Clonalité
    • 39
    Polyclonal
    Conjugué
    • 17
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp GALR2 est non-conjugé
    Application
    • 33
    • 18
    • 13
    • 13
    • 9
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC)
     Réactivité croisée
    Humain, Souris, Rat
    Attributs du produit
    Rabbit Polyclonal antibody to Galanin Receptor 2 (galanin receptor 2)
    Galanin Receptor 2 antibody [C1C2], Internal
    Purification
    Purified by antigen-affinity chromatography.
    Immunogène
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human GALR2. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product GALR2 Anticorps primaire
  • Indications d'application
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Commentaires

    Positive Control: 293T , H1299

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    Agent conservateur
    Thimerosal (Merthiolate)
    Précaution d'utilisation
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Antigène
    GALR2 (Galanin Receptor 2 (GALR2))
    Autre désignation
    galanin receptor 2 (GALR2 Produits)
    Synonymes
    anticorps GALNR2, anticorps mGalR, anticorps GALR2, anticorps GAL2-R, anticorps GALR-2, anticorps galanin receptor 2, anticorps transcription regulator. LacI family, raffinose related, anticorps DNA-binding transcriptional regulator GalR, anticorps galactose operon repressor, anticorps galanin receptor type 2, anticorps GALR2, anticorps Galr2, anticorps LOC100037698, anticorps rafR, anticorps galR2, anticorps LOC103690156
    Sujet
    Galanin is an important neuromodulator present in the brain, gastrointestinal system, and hypothalamopituitary axis. It is a 30-amino acid non-C-terminally amidated peptide that potently stimulates growth hormone secretion, inhibits cardiac vagal slowing of heart rate, abolishes sinus arrhythmia, and inhibits postprandial gastrointestinal motility. The actions of galanin are mediated through interaction with specific membrane receptors that are members of the 7-transmembrane family of G protein-coupled receptors. GALR2 interacts with the N-terminal residues of the galanin peptide. The primary signaling mechanism for GALR2 is through the phospholipase C/protein kinase C pathway (via Gq), in contrast to GALR1, which communicates its intracellular signal by inhibition of adenylyl cyclase through Gi. However, it has been demonstrated that GALR2 couples efficiently to both the Gq and Gi proteins to simultaneously activate 2 independent signal transduction pathways.

    Cellular Localization: Cell membrane, Multi-pass membrane protein
    Poids moléculaire
    42 kDa
    ID gène
    8811
    UniProt
    O43603
    Pathways
    cAMP Metabolic Process, Inositol Metabolic Process, Feeding Behaviour
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