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PTGS2 anticorps (C-Term)

PTGS2 Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2854824
  • Antigène Voir toutes PTGS2 Anticorps
    PTGS2 (Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS2))
    Épitope
    • 16
    • 15
    • 11
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 105
    • 59
    • 44
    • 21
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 94
    • 21
    • 2
    Lapin
    Clonalité
    • 88
    • 29
    Polyclonal
    Conjugué
    • 66
    • 9
    • 8
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Cet anticorp PTGS2 est non-conjugé
    Application
    • 103
    • 42
    • 37
    • 32
    • 27
    • 26
    • 22
    • 19
    • 16
    • 14
    • 8
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
     Réactivité croisée
    Humain, Souris, Rat
    Attributs du produit
    Rabbit Polyclonal antibody to COX2 (prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase))
    COX2 antibody [C3], C-term
    Purification
    Purified by antigen-affinity chromatography.
    Immunogène
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human COX2. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product PTGS2 Anticorps primaire
  • Indications d'application
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Commentaires

    Positive Control: RAW264.7 (0.1 μg/ml PMA treatment for 16 hr and 1 μg/ml LPS treatment for 24 hr) , THP-1 (100 ng/ml PMA treatment for 16 hr and 1000 ng/ml LPS treatment for 24 hr)

    Validation: Orthogonal

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.42 mg/mL
    Buffer
    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Antigène
    PTGS2 (Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS2))
    Autre désignation
    prostaglandin-endoperoxide synthase 2 (PTGS2 Produits)
    Synonymes
    anticorps COX-2, anticorps COX2, anticorps GRIPGHS, anticorps PGG/HS, anticorps PGHS-2, anticorps PHS-2, anticorps hCox-2, anticorps Cox-2, anticorps Pghs2, anticorps TIS10, anticorps Cox2, anticorps cox-2, anticorps CEF147, anticorps PGHS2, anticorps PHSII, anticorps cox2, anticorps gripghs, anticorps pgg/hs, anticorps pghs-2, anticorps phs-2, anticorps PTGS2, anticorps hcox-2, anticorps fj02a10, anticorps ptgs2, anticorps unp1239, anticorps wu:fj02a10, anticorps zCOX-2, anticorps si:dkey-97o5.6, anticorps prostaglandin-endoperoxide synthase 2, anticorps prostaglandin G/H synthase 2, anticorps prostaglandin-endoperoxide synthase 2S homeolog, anticorps prostaglandin-endoperoxide synthase 2a, anticorps prostaglandin-endoperoxide synthase 2b, anticorps PTGS2, anticorps Ptgs2, anticorps LOC100136456, anticorps ptgs2.S, anticorps ptgs2, anticorps ptgs2a, anticorps ptgs2b
    Sujet
    Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis.

    Poids moléculaire
    69 kDa
    ID gène
    5743
    UniProt
    P35354
    Pathways
    Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
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