MUC2 anticorps (C-Term)

N° du produit ABIN2854828

Détail du produit anti-MUC2 anticorps

Antigène: MUC2 (Mucin 2, Oligomeric Mucus/gel-Forming (MUC2))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MUC2 est non-conjugé

Application: Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Fluorescence in situ hybridization (FISH)

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Rabbit Polyclonal antibody to MUC2 (mucin 2, oligomeric mucus/gel-forming)
MUC2 antibody [C3], C-term

Purification: Purified by antigen-affinity chromatography.

Immunogène: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human MUC2. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Validation: Orthogonal

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Références pour anticorps anti-MUC2 (ABIN2854828)

Toubai, Fujiwara, Rossi, Riwes, Tamaki, Zajac, Liu, Mathew, Byun, Oravecz-Wilson, Matsuda, Sun, Peltier, Wu, Chen, Seregin, Henig, Kim, Brabbs, Pennathur, Chen, Reddy: "Host NLRP6 exacerbates graft-versus-host disease independent of gut microbial composition." dans: Nature microbiology, Vol. 4, Issue 5, pp. 800-812, (2019) (PubMed).

Détails sur MUC2

Antigène: MUC2 (Mucin 2, Oligomeric Mucus/gel-Forming (MUC2))

Autre désignation: mucin 2, oligomeric mucus/gel-forming (MUC2 Produits)

Synonymes: anticorps 2010015E03Rik, anticorps MCM, anticorps wnn, anticorps MLP, anticorps MUC-2, anticorps SMUC, anticorps HH-Muc, anticorps mucin 2, anticorps mucin 2, oligomeric mucus/gel-forming, anticorps mucin-2, anticorps Muc2, anticorps MUC2, anticorps LOC100724045

Sujet: This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins produced by many epithelial tissues. The protein encoded by this gene is secreted and forms an insoluble mucous barrier that protects the gut lumen. The protein polymerizes into a gel of which 80 % is composed of oligosaccharide side chains by weight. The protein features a central domain containing tandem repeats rich in threonine and proline that varies between 50 and 115 copies in different individuals. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.

Cellular Localization: Secreted

Poids moléculaire: 540 kDa

ID gène: 4583

UniProt: Q02817