Retinoic Acid Receptor beta anticorps

N° du produit ABIN2854857

Détail du produit anti-Retinoic Acid Receptor beta anticorps

Antigène: Retinoic Acid Receptor beta (RARB) (Retinoic Acid Receptor, beta (RARB))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Retinoic Acid Receptor beta est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Humain

Attributs du produit: Rabbit Polyclonal antibody to Retinoic Acid Receptor beta (retinoic acid receptor, beta)
Retinoic Acid Receptor beta antibody

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human Retinoic Acid Receptor beta. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: HepG2

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.97 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur Retinoic Acid Receptor beta

Antigène: Retinoic Acid Receptor beta (RARB) (Retinoic Acid Receptor, beta (RARB))

Autre désignation: retinoic acid receptor beta (RARB Produits)

Synonymes: anticorps RARB, anticorps nRARs, anticorps HAP, anticorps NR1B2, anticorps RRB2, anticorps A830025K23, anticorps Hap, anticorps Nr1b2, anticorps RARbeta2, anticorps RARBETA, anticorps retinoic acid receptor beta, anticorps retinoic acid receptor, beta, anticorps RARB, anticorps Rarb

Sujet: This gene encodes retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating gene expression. The gene was first identified in a hepatocellular carcinoma where it flanks a hepatitis B virus integration site. The gene expresses at least two transcript variants, one additional transcript has been described, but its full length nature has not been determined.

Cellular Localization: Isoform Beta-1: Nucleus , Isoform Beta-2: Nucleus , Isoform Beta-4: Cytoplasm

Poids moléculaire: 50 kDa

ID gène: 5915

UniProt: P10826

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway