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IL3RA anticorps

IL3RA Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2855090
  • Antigène Voir toutes IL3RA Anticorps
    IL3RA (Interleukin 3 Receptor, alpha (IL3RA))
    Reactivité
    • 90
    • 29
    • 3
    Humain
    Hôte
    • 47
    • 46
    • 6
    • 1
    Lapin
    Clonalité
    • 55
    • 44
    • 1
    Polyclonal
    Conjugué
    • 48
    • 11
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp IL3RA est non-conjugé
    Application
    • 61
    • 60
    • 19
    • 15
    • 13
    • 13
    • 12
    • 8
    • 8
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
     Réactivité croisée
    Humain
    Attributs du produit
    Rabbit Polyclonal antibody to IL3 Receptor alpha (interleukin 3 receptor, alpha (low affinity))
    IL3 Receptor alpha antibody [N2C2], Internal
    Purification
    Purified by antigen-affinity chromatography.
    Immunogène
    Recombinant protein encompassing a sequence within the center region of human IL3 Receptor alpha. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product IL3RA Anticorps primaire
  • Indications d'application
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Commentaires

    Validation: Overexpression

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.2 mg/mL
    Buffer
    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Antigène
    IL3RA (Interleukin 3 Receptor, alpha (IL3RA))
    Autre désignation
    interleukin 3 receptor subunit alpha (IL3RA Produits)
    Synonymes
    anticorps CD123, anticorps IL3R, anticorps IL3RAY, anticorps IL3RX, anticorps IL3RY, anticorps hIL-3Ra, anticorps CDw123, anticorps SUT-1, anticorps Cyrl, anticorps interleukin 3 receptor subunit alpha, anticorps interleukin 3 receptor, alpha chain, anticorps IL3RA, anticorps Il3ra
    Sujet
    The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y.

    Cellular Localization: Membrane, Single-pass type I membrane protein
    Poids moléculaire
    43 kDa
    ID gène
    3563
    UniProt
    P26951
    Pathways
    Signalistation JAK/STAT
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