PAX8 anticorps (Paired Box 8) (Center)

Details for Product anti-PAX8 Antibody No. ABIN2855097
Antigène
  • PAX8
  • XPax-8
  • XPax8
  • pax-8
  • PAX-8
  • Pax-8
  • paired box 8
  • paired box 8 L homeolog
  • PAX8
  • pax8
  • Pax8
  • pax8.L
Épitope
Center
56
23
15
12
12
7
7
6
4
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Reactivité
Humain, Rat (Rattus)
228
60
51
14
9
9
8
7
4
3
2
1
1
Hôte
Lapin
99
92
38
Clonalité
Polyclonal
Conjugué
Cet anticorp PAX8 est non-conjugé
11
7
6
6
6
6
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
Application
Chromatin Immunoprecipitation (ChIP), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
198
100
73
66
61
33
19
6
3
2
2
1
1
1
1
Options
Immunogène Recombinant protein encompassing a sequence within the center region of human PAX8. The exact sequence is proprietary.
Isotype IgG
Attributs du produit Rabbit Polyclonal antibody to PAX8 (paired box 8)
PAX8 antibody
Purification Purified by antigen-affinity chromatography.
Plasmids, Primers & others Plasmids, Primers & others PAX8 products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation PAX8 (PAX8 Antibody Extrait)
Sujet This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternateively spliced transcript variants encoding different isoforms have been described.

Cellular Localization: Nucleus
Poids moléculaire 48 kDa
ID gène 7849
Pathways Thyroid Hormone Synthesis, Regulation of Hormone Metabolic Process, Stem Cell Maintenance, Tube Formation
Indications d'application Suggested dilution Reference ChIP assay Assay-dependent dilution ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Immunoprecipitation 1:500-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceChIP assayAssay-dependent dilution ICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Immunoprecipitation1:500-1:1000* Western blot1:500-1:3000*
Commentaires

Positive Control: 293T
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
Agent conservateur Thimerosal (Merthiolate)
Précaution d'utilisation This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock -20 °C
Stockage commentaire Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Images (Fournisseur)
Immunofluorescence (IF) image for anti-Paired Box 8 (PAX8) (Center) antibody (ABIN2855097) ICC/IF Image Immunofluorescence analysis of paraformaldehyde-fixed A549, using PAX8, ...
Immunohistochemistry (IHC) image for anti-Paired Box 8 (PAX8) (Center) antibody (ABIN2855097) IHC-P Image PAX8 antibody detects PAX8 protein at cytosol and nucleus on rat thyroid ...
Immunoprecipitation (IP) image for anti-Paired Box 8 (PAX8) (Center) antibody (ABIN2855097) IP Image PAX8 antibody immunoprecipitates PAX8 protein in IP experiments. IP Sample: ...
Western Blotting (WB) image for anti-Paired Box 8 (PAX8) (Center) antibody (ABIN2855097) WB Image Sample(30 ug whole cell lysate) A:293T 10% SDS PAGE antibody diluted at 1:1000
Chromatin Immunoprecipitation (ChIP) image for anti-Paired Box 8 (PAX8) (Center) antibody (ABIN2855097) ChIP Image PAX8 antibody immunoprecipitates PAX8 protein-DNA in ChIP experiments. ChI...
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