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LTBP4 anticorps (N-Term)

LTBP4 Reactivité: Humain WB, IF, IHC (p), ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2855142
  • Antigène Voir toutes LTBP4 Anticorps
    LTBP4 (Latent Transforming Growth Factor beta Binding Protein 4 (LTBP4))
    Épitope
    • 5
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 15
    • 2
    • 2
    • 2
    • 1
    Humain
    Hôte
    • 15
    Lapin
    Clonalité
    • 15
    Polyclonal
    Conjugué
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp LTBP4 est non-conjugé
    Application
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
     Réactivité croisée
    Humain, Souris
    Attributs du produit
    Rabbit Polyclonal antibody to LTBP4 (latent transforming growth factor beta binding protein 4)
    LTBP4 antibody [N1N2], N-term
    Purification
    Purified by antigen-affinity chromatography.
    Immunogène
    Recombinant protein encompassing a sequence within the N-terminus region of human LTBP4. The exact sequence is proprietary.
    Isotype
    IgG
  • Indications d'application
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Commentaires

    Positive Control: Mouse brain , Positive Control: Mouse brain

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.07 mg/mL
    Buffer
    1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Antigène
    LTBP4 (Latent Transforming Growth Factor beta Binding Protein 4 (LTBP4))
    Autre désignation
    latent transforming growth factor beta binding protein 4 (LTBP4 Produits)
    Synonymes
    anticorps ARCL1C, anticorps LTBP-4, anticorps LTBP4L, anticorps LTBP4S, anticorps 2310046A13Rik, anticorps latent transforming growth factor beta binding protein 4, anticorps LTBP4, anticorps ltbp4, anticorps Ltbp4
    Sujet
    Transforming growth factor-beta, or TGFB (see TGFB1, MIM 190180), remains biologically latent after secretion, blocked from activity by its N-terminal propeptide (the latency-associated peptide, or LAP). TGFB is activated by its dissociation from LAP. The latent form of TGFB is secreted in association with a latent TGFB-binding protein, or LTBP (see LTBP1, MIM 150390), and assembled into the extracellular matrix. LTBPs are mainly composed of epidermal growth factor (EGF, MIM 131530)-like repeats and protein domains with 8-cysteine repeats, both of which are also found in fibrillins (e.g., MIM 134797). See Oklu and Hesketh (2000) [PubMed 11104663] for a review of the LTBP gene family.[supplied by OMIM]

    Cellular Localization: Secreted , extracellular space , extracellular matrix
    Poids moléculaire
    173 kDa
    ID gène
    8425
    UniProt
    Q8N2S1
    Pathways
    Hormone Transport, Growth Factor Binding
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