MMP12 anticorps
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- Antigène Voir toutes MMP12 Anticorps
- MMP12 (Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MMP12 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Réactivité croisée
- Humain
- Attributs du produit
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Rabbit polyclonal antibody to MMP12 (matrix metallopeptidase 12 (macrophage elastase))
MMP12 antibody [N3C3] - Purification
- Purified by antigen-affinity chromatography.
- Immunogène
- Recombinant protein encompassing a sequence within the center region of human MMP12. The exact sequence is proprietary.
- Isotype
- IgG
- Top Product
- Discover our top product MMP12 Anticorps primaire
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- Indications d'application
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Commentaires
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Positive Control: 293T
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
- Agent conservateur
- Thimerosal (Merthiolate)
- Précaution d'utilisation
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Antigène
- MMP12 (Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12))
- Autre désignation
- matrix metallopeptidase 12 (MMP12 Produits)
- Synonymes
- anticorps MMP12, anticorps AV378681, anticorps Mmel, anticorps Mme, anticorps HME, anticorps ME, anticorps MME, anticorps MMP-12, anticorps matrix metallopeptidase 12, anticorps MMP12, anticorps Mmp12
- Sujet
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Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. It is thought that the protein encoded by this gene is cleaved at both ends to yield the active enzyme, but this processing has not been fully described. The enzyme degrades soluble and insoluble elastin. It may play a role in aneurysm formation and studies in mice suggest a role in the development of emphysema. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
Cellular Localization: Secreted , extracellular space , extracellular matrix - Poids moléculaire
- 54 kDa
- ID gène
- 4321
- UniProt
- P39900
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