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MMP12 anticorps

MMP12 Reactivité: Humain WB, IHC, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2855520
  • Antigène Voir toutes MMP12 Anticorps
    MMP12 (Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12))
    Reactivité
    • 72
    • 35
    • 35
    • 4
    • 1
    Humain
    Hôte
    • 90
    • 3
    • 2
    • 1
    Lapin
    Clonalité
    • 81
    • 15
    Polyclonal
    Conjugué
    • 41
    • 17
    • 13
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MMP12 est non-conjugé
    Application
    • 85
    • 36
    • 34
    • 13
    • 11
    • 11
    • 7
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
     Réactivité croisée
    Humain
    Attributs du produit
    Rabbit polyclonal antibody to MMP12 (matrix metallopeptidase 12 (macrophage elastase))
    MMP12 antibody [N3C3]
    Purification
    Purified by antigen-affinity chromatography.
    Immunogène
    Recombinant protein encompassing a sequence within the center region of human MMP12. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product MMP12 Anticorps primaire
  • Indications d'application
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Commentaires

    Positive Control: 293T

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    Agent conservateur
    Thimerosal (Merthiolate)
    Précaution d'utilisation
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Antigène
    MMP12 (Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12))
    Autre désignation
    matrix metallopeptidase 12 (MMP12 Produits)
    Synonymes
    anticorps MMP12, anticorps AV378681, anticorps Mmel, anticorps Mme, anticorps HME, anticorps ME, anticorps MME, anticorps MMP-12, anticorps matrix metallopeptidase 12, anticorps MMP12, anticorps Mmp12
    Sujet
    Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. It is thought that the protein encoded by this gene is cleaved at both ends to yield the active enzyme, but this processing has not been fully described. The enzyme degrades soluble and insoluble elastin. It may play a role in aneurysm formation and studies in mice suggest a role in the development of emphysema. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

    Cellular Localization: Secreted , extracellular space , extracellular matrix
    Poids moléculaire
    54 kDa
    ID gène
    4321
    UniProt
    P39900
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