COL1A2 anticorps (C-Term)
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- Antigène Voir toutes COL1A2 Anticorps
- COL1A2 (Collagen, Type I, alpha 2 (COL1A2))
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Épitope
- C-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp COL1A2 est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Réactivité croisée
- Humain, Souris, Poisson zèbre (Danio rerio)
- Attributs du produit
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Rabbit Polyclonal antibody to COL1A2 (collagen, type I, alpha 2)
COL1A2 antibody [C2C3], C-term - Purification
- Purified by antigen-affinity chromatography.
- Classe de qualité
- KO Validated
- Immunogène
- Recombinant protein encompassing a sequence within the C-terminus region of human COL1A2. The exact sequence is proprietary.
- Isotype
- IgG
- Top Product
- Discover our top product COL1A2 Anticorps primaire
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- Indications d'application
- WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Commentaires
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Validation: KO/KD, Orthogonal, Overexpression
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 2.61 mg/mL
- Buffer
- 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Antigène
- COL1A2 (Collagen, Type I, alpha 2 (COL1A2))
- Autre désignation
- collagen type I alpha 2 chain (COL1A2 Produits)
- Synonymes
- anticorps AA960264, anticorps AI325291, anticorps Col1a-2, anticorps Cola-2, anticorps Cola2, anticorps oim, anticorps OI4, anticorps Gas-6, anticorps alpha2(I), anticorps hm:zehn2357, anticorps wu:fa98d05, anticorps wu:fa99g10, anticorps wu:fb04c08, anticorps wu:fb11d06, anticorps zehn2357, anticorps coagulation factor II, thrombin, anticorps collagen, type I, alpha 2, anticorps collagen type I alpha 2 chain, anticorps collagen type I alpha 2 L homeolog, anticorps growth arrest specific 6, anticorps F2, anticorps Col1a2, anticorps col1a2.L, anticorps COL1A2, anticorps Gas6, anticorps col1a2
- Sujet
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This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity. Three transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish]
Cellular Localization: Secreted , extracellular space , extracellular matrix - Poids moléculaire
- 129 kDa
- ID gène
- 1278
- UniProt
- P08123
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