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COL1A2 anticorps (C-Term)

KO Validated COL1A2 Reactivité: Humain WB, IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2855530
  • Antigène Voir toutes COL1A2 Anticorps
    COL1A2 (Collagen, Type I, alpha 2 (COL1A2))
    Épitope
    • 13
    • 8
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 61
    • 22
    • 18
    • 8
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 59
    • 8
    • 6
    • 2
    Lapin
    Clonalité
    • 67
    • 8
    Polyclonal
    Conjugué
    • 44
    • 8
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp COL1A2 est non-conjugé
    Application
    • 56
    • 31
    • 24
    • 15
    • 10
    • 10
    • 8
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
     Réactivité croisée
    Humain, Souris, Poisson zèbre (Danio rerio)
    Attributs du produit
    Rabbit Polyclonal antibody to COL1A2 (collagen, type I, alpha 2)
    COL1A2 antibody [C2C3], C-term
    Purification
    Purified by antigen-affinity chromatography.
    Classe de qualité
    KO Validated
    Immunogène
    Recombinant protein encompassing a sequence within the C-terminus region of human COL1A2. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product COL1A2 Anticorps primaire
  • Indications d'application
    WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Commentaires

    Validation: KO/KD, Orthogonal, Overexpression

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    2.61 mg/mL
    Buffer
    1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Antigène
    COL1A2 (Collagen, Type I, alpha 2 (COL1A2))
    Autre désignation
    collagen type I alpha 2 chain (COL1A2 Produits)
    Synonymes
    anticorps AA960264, anticorps AI325291, anticorps Col1a-2, anticorps Cola-2, anticorps Cola2, anticorps oim, anticorps OI4, anticorps Gas-6, anticorps alpha2(I), anticorps hm:zehn2357, anticorps wu:fa98d05, anticorps wu:fa99g10, anticorps wu:fb04c08, anticorps wu:fb11d06, anticorps zehn2357, anticorps coagulation factor II, thrombin, anticorps collagen, type I, alpha 2, anticorps collagen type I alpha 2 chain, anticorps collagen type I alpha 2 L homeolog, anticorps growth arrest specific 6, anticorps F2, anticorps Col1a2, anticorps col1a2.L, anticorps COL1A2, anticorps Gas6, anticorps col1a2
    Sujet
    This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity. Three transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish]

    Cellular Localization: Secreted , extracellular space , extracellular matrix
    Poids moléculaire
    129 kDa
    ID gène
    1278
    UniProt
    P08123
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