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TXNRD1 anticorps

TXNRD1 Reactivité: Humain WB, IHC (p), ICC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2855577
  • Antigène Voir toutes TXNRD1 Anticorps
    TXNRD1 (Thioredoxin Reductase 1 (TXNRD1))
    Reactivité
    • 44
    • 28
    • 26
    Humain
    Hôte
    • 41
    • 5
    • 1
    Lapin
    Clonalité
    • 35
    • 12
    Polyclonal
    Conjugué
    • 21
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TXNRD1 est non-conjugé
    Application
    • 33
    • 14
    • 14
    • 12
    • 9
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (IF)
     Réactivité croisée
    Humain, Souris
    Attributs du produit
    Rabbit polyclonal antibody to TrxR1 (thioredoxin reductase 1)
    TrxR1 antibody [N1N3]
    Purification
    Purified by antigen-affinity chromatography.
    Immunogène
    Recombinant protein encompassing a sequence within the center region of human TrxR1. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product TXNRD1 Anticorps primaire
  • Indications d'application
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Commentaires

    Positive Control: HepG2

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    Agent conservateur
    Thimerosal (Merthiolate)
    Précaution d'utilisation
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Antigène
    TXNRD1 (Thioredoxin Reductase 1 (TXNRD1))
    Autre désignation
    thioredoxin reductase 1 (TXNRD1 Produits)
    Synonymes
    anticorps TrxR1, anticorps cb682, anticorps fb83a08, anticorps wu:fb83a08, anticorps GB14972, anticorps MGC85342, anticorps NADPH-dependent thioredoxin reductase C, anticorps T32G6.20, anticorps T32G6_20, anticorps GRIM-12, anticorps TR, anticorps TR1, anticorps TRXR1, anticorps TXNR, anticorps Tr, anticorps thioredoxin reductase 1, anticorps thioredoxin reductase 1 L homeolog, anticorps NADPH-dependent thioredoxin reductase C, anticorps ThioRedoXin Reductase, anticorps TXNRD1, anticorps txnrd1, anticorps Trxr-1, anticorps txnrd1.L, anticorps NTRC, anticorps trxr-1, anticorps Txnrd1
    Sujet
    This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms.

    Cellular Localization: Cytoplasm , Isoform 4: Cytoplasm , Nucleus , Isoform 5: Cytoplasm
    Poids moléculaire
    71 kDa
    ID gène
    7296
    UniProt
    Q16881
    Pathways
    Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Cell RedoxHomeostasis
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