ACVR1C/ALK7 anticorps (Center)

N° du produit ABIN2855632

Détail du produit anti-ACVR1C/ALK7 anticorps

Antigène: ACVR1C/ALK7 (ACVR1C) (Activin Receptor Type 1C (ACVR1C))

Épitope: Center

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ACVR1C/ALK7 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Souris, Rat (Rattus), Boeuf (Vache)

Réactivité croisée (Details): Mouse (93 %), Rat (94 %), Bovine (97 %)

Attributs du produit: Rabbit Polyclonal antibody to Activin A Receptor Type IC (activin A receptor, type IC)
Activin A Receptor Type IC antibody

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human Activin A Receptor Type IC. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

Commentaires:

Positive Control: HepG2

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS, 1 % BSA, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur ACVR1C/ALK7

Antigène: ACVR1C/ALK7 (ACVR1C) (Activin Receptor Type 1C (ACVR1C))

Autre désignation: Activin A Receptor Type IC (ACVR1C Produits)

Synonymes: anticorps ACVRLK7, anticorps ALK7, anticorps Alk-7, anticorps C230097P10, anticorps Alk7, anticorps habrec1, anticorps activin A receptor type 1C, anticorps activin A receptor, type IC, anticorps ACVR1C, anticorps Acvr1c

Sujet: ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM]

Cellular Localization: Membrane

Poids moléculaire: 55 kDa

ID gène: 130399

Pathways: Negative Regulation of Hormone Secretion, Positive Regulation of Endopeptidase Activity