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CKMT1B anticorps

CKMT1B Reactivité: Humain WB, IHC (p), IHC (wm) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2855669
  • Antigène Voir toutes CKMT1B Anticorps
    CKMT1B (Creatine Kinase, Mitochondrial 1B (CKMT1B))
    Reactivité
    • 30
    • 19
    • 17
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 25
    • 5
    Lapin
    Clonalité
    • 27
    • 3
    Polyclonal
    Conjugué
    • 16
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CKMT1B est non-conjugé
    Application
    • 29
    • 13
    • 13
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Whole Mount) (IHC (wm))
     Réactivité croisée
    Humain, Poisson zèbre (Danio rerio)
    Attributs du produit
    Rabbit Polyclonal antibody to Creatine kinase 1B (creatine kinase, mitochondrial 1B)
    Creatine kinase 1B antibody
    Purification
    Purified by antigen-affinity chromatography.
    Immunogène
    Recombinant protein encompassing a sequence within the center region of human Creatine kinase MT. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product CKMT1B Anticorps primaire
  • Indications d'application
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Commentaires

    Positive Control: H1299 , HeLaS3

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    Agent conservateur
    Thimerosal (Merthiolate)
    Précaution d'utilisation
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Antigène
    CKMT1B (Creatine Kinase, Mitochondrial 1B (CKMT1B))
    Autre désignation
    creatine kinase, mitochondrial 1B (CKMT1B Produits)
    Synonymes
    anticorps CKMT, anticorps CKMT1, anticorps UMTCK, anticorps ckmt, anticorps ckmt1, anticorps umtck, anticorps CKMT1A, anticorps creatine kinase, mitochondrial 1B, anticorps creatine kinase, mitochondrial 1B S homeolog, anticorps creatine kinase, mitochondrial 1B L homeolog, anticorps CKMT1B, anticorps ckmt1b.S, anticorps ckmt1b.L, anticorps ckmt1b
    Sujet
    Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase, this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80 % homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins.

    Cellular Localization: Mitochondrion inner membrane, Peripheral membrane protein, Intermembrane side
    Poids moléculaire
    47 kDa
    ID gène
    1159
    UniProt
    P12532
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