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EPAS1 anticorps

EPAS1 Reactivité: Humain WB, ChIP Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2855683
  • Antigène Voir toutes EPAS1 Anticorps
    EPAS1 (Endothelial PAS Domain Protein 1 (EPAS1))
    Reactivité
    • 92
    • 49
    • 43
    • 18
    • 17
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 100
    • 11
    • 1
    • 1
    Lapin
    Clonalité
    • 92
    • 21
    Polyclonal
    Conjugué
    • 57
    • 14
    • 7
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp EPAS1 est non-conjugé
    Application
    • 92
    • 47
    • 32
    • 24
    • 15
    • 14
    • 14
    • 13
    • 13
    • 12
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)
     Réactivité croisée
    Humain, Poisson zèbre (Danio rerio)
    Attributs du produit
    Rabbit Polyclonal antibody to HIF2 alpha (endothelial PAS domain protein 1)
    HIF2 alpha antibody [N1N3]
    Purification
    Purified by antigen-affinity chromatography.
    Immunogène
    Recombinant protein encompassing a sequence within the center region of human HIF2 alpha. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product EPAS1 Anticorps primaire
  • Indications d'application
    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Commentaires

    Positive Control: HepG2 (1% O2 treatment for 24hr)

    Validation: Orthogonal

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Ko, Tsai, Tseng, Cheng, Huang, Wu, Chung, Hsieh, Sun, Hwang, Yuh, Huang, Pai, Tzou, Hu: "Integration of CNS survival and differentiation by HIF2α." dans: Cell death and differentiation, Vol. 18, Issue 11, pp. 1757-70, (2012) (PubMed).

  • Antigène
    EPAS1 (Endothelial PAS Domain Protein 1 (EPAS1))
    Autre désignation
    endothelial PAS domain protein 1 (EPAS1 Produits)
    Synonymes
    anticorps EPAS1, anticorps ECYT4, anticorps HIF2A, anticorps HLF, anticorps MOP2, anticorps PASD2, anticorps bHLHe73, anticorps HIF-2alpha, anticorps HRF, anticorps Hif2a, anticorps bhlhe73, anticorps ecyt4, anticorps hif2, anticorps hif2a, anticorps hif2alpha, anticorps hlf, anticorps mop2, anticorps pasd2, anticorps EPAS, anticorps EPAS-1, anticorps endothelial PAS domain protein 1, anticorps endothelial PAS domain protein 1 L homeolog, anticorps EPAS1, anticorps epas1, anticorps Epas1, anticorps epas1.L
    Sujet
    This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4.

    Cellular Localization: Nucleus
    Poids moléculaire
    96 kDa
    ID gène
    2034
    UniProt
    Q99814
    Pathways
    Signaling Events mediated by VEGFR1 and VEGFR2, L'effet Warburg
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