Haptoglobin anticorps
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- Antigène Voir toutes Haptoglobin (HP) Anticorps
- Haptoglobin (HP)
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Haptoglobin est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Réactivité croisée
- Humain
- Attributs du produit
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Rabbit Polyclonal antibody to Haptoglobin (haptoglobin)
Haptoglobin antibody - Purification
- Purified by antigen-affinity chromatography.
- Immunogène
- Recombinant protein encompassing a sequence within the center region of human Haptoglobin. The exact sequence is proprietary.
- Isotype
- IgG
- Top Product
- Discover our top product HP Anticorps primaire
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- Indications d'application
- WB: 1:5000-1:30000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
- Agent conservateur
- Thimerosal (Merthiolate)
- Précaution d'utilisation
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Antigène
- Haptoglobin (HP)
- Autre désignation
- haptoglobin (HP Produits)
- Synonymes
- anticorps HP, anticorps wu:fb64e01, anticorps BP, anticorps HP2ALPHA2, anticorps HPA1S, anticorps HP-1, anticorps HPR, anticorps Zonulin, anticorps haptoglobin, anticorps haptoglobin-like, anticorps HP, anticorps hp, anticorps Hp, anticorps LOC479668, anticorps LOC101102413
- Sujet
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This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene.
Cellular Localization: Secreted - Poids moléculaire
- 45 kDa
- ID gène
- 3240
- UniProt
- P00738
- Pathways
- Transition Metal Ion Homeostasis
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