ARG2 anticorps (Center)

N° du produit ABIN2855753

Détail du produit anti-ARG2 anticorps

Antigène: ARG2 (Arginase, Type II (ARG2))

Épitope: Center

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARG2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Rabbit Polyclonal antibody to Arginase II (arginase, type II)
Arginase II antibody

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human ARG2. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: mouse kidney , 293T cytoplasm extract , NT2D1

Validation: Orthogonal

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.32 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Références pour anticorps anti-ARG2 (ABIN2855753)

Polis, Srikanth, Gurevich, Gil-Henn, Samson: "L-Norvaline, a new therapeutic agent against Alzheimer's disease." dans: Neural regeneration research, Vol. 14, Issue 9, pp. 1562-1572, (2019) (PubMed).

Polis, Srikanth, Elliott, Gil-Henn, Samson: "L-Norvaline Reverses Cognitive Decline and Synaptic Loss in a Murine Model of Alzheimer's Disease." dans: Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, Vol. 15, Issue 4, pp. 1036-1054, (2019) (PubMed).

Détails sur ARG2

Antigène: ARG2 (Arginase, Type II (ARG2))

Autre désignation: arginase 2 (ARG2 Produits)

Synonymes: anticorps AII, anticorps AU022422, anticorps zgc:65793, anticorps zgc:85630, anticorps wu:fb67g02, anticorps ARG2, anticorps LeARG2, anticorps arg1, anticorps arg3, anticorps arg2, anticorps arg2-c, anticorps arg2-b, anticorps arginase 2, anticorps arginase type II, anticorps arginase 2 L homeolog, anticorps arginase 2 S homeolog, anticorps ARG2, anticorps Arg2, anticorps arg2, anticorps arg2.L, anticorps arg2.S

Sujet: Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exists (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type II isoform encoded by this gene, is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney. The physiologic role of this isoform is poorly understood, it is thought to play a role in nitric oxide and polyamine metabolism. Transcript variants of the type II gene resulting from the use of alternative polyadenylation sites have been described.

Cellular Localization: Mitochondrion

Poids moléculaire: 39 kDa

ID gène: 384

UniProt: P78540