CYP46A1 anticorps (Center)

N° du produit ABIN2856057

Détail du produit anti-CYP46A1 anticorps

Antigène: CYP46A1 (Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 (CYP46A1))

Épitope: Center

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CYP46A1 est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Humain

Réactivité croisée (Details): Human (100 %)

Attributs du produit: Rabbit Polyclonal antibody to CYP46A1 (cytochrome P450, family 46, subfamily A, polypeptide 1)
CYP46A1 antibody [N1C2]

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human CYP46A1. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*

Commentaires:

Positive Control: Mouse brain

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur CYP46A1

Antigène: CYP46A1 (Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 (CYP46A1))

Autre désignation: CYP46A1 (CYP46A1 Produits)

Synonymes: anticorps CP46, anticorps CYP46, anticorps CYP46A1, anticorps zgc:109896, anticorps MGC147389, anticorps Cyp46, anticorps cytochrome P450 family 46 subfamily A member 1, anticorps cytochrome P450 family 46 subfamily A member 1 L homeolog, anticorps cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 1, anticorps cytochrome P450, family 46, anticorps cytochrome P450 46A1, anticorps cytochrome P450, family 46, subfamily a, polypeptide 1, anticorps cholesterol 24-hydroxylase, anticorps cytochrome P450, family 46, subfamily A, polypeptide 1, anticorps CYP46A1, anticorps cyp46a1.L, anticorps cyp46a1.1, anticorps cyp46a1, anticorps PTRG_08343, anticorps PTRG_09667, anticorps Cyp46a1, anticorps Sgly_1093

Sujet: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism.

Cellular Localization: Endoplasmic reticulum membrane , Microsome membrane

Poids moléculaire: 57 kDa

ID gène: 10858