CYP24A1 anticorps (Center)

N° du produit ABIN2856211

Détail du produit anti-CYP24A1 anticorps

Antigène: CYP24A1 (Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 (CYP24A1))

Épitope: Center

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CYP24A1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Souris, Rat (Rattus)

Réactivité croisée (Details): mouse (87 %), Rat (88 %)

Attributs du produit: Rabbit Polyclonal antibody to CYP24A1 (cytochrome P450, family 24, subfamily A, polypeptide 1)
CYP24A1 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human CYP24A1. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

Commentaires:

Positive Control: 293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur CYP24A1

Antigène: CYP24A1 (Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 (CYP24A1))

Autre désignation: CYP24A1 (CYP24A1 Produits)

Synonymes: anticorps CP24, anticorps CYP24, anticorps HCAI, anticorps P450-CC24, anticorps 24-OHase, anticorps Cyp24, anticorps 25-hydroxyvitaminD324-hydroxylase, anticorps VITD12, anticorps CP450CC24, anticorps cytochrome P450 family 24 subfamily A member 1, anticorps cytochrome P450, family 24, subfamily a, polypeptide 1, anticorps cytochrome P450, family 24, subfamily A, polypeptide 1, anticorps CYP24A1, anticorps Cyp24a1

Sujet: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Cellular Localization: Mitochondrion

Poids moléculaire: 59 kDa

ID gène: 1591

Pathways: Metabolism of Steroid Hormones and Vitamin D