STAM anticorps (Center)

N° du produit ABIN2856220

Détail du produit anti-STAM anticorps

Antigène: STAM (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 1 (STAM))

Épitope: Center

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STAM est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Souris, Xenopus laevis, Boeuf (Vache), Xenopus tropicalis

Réactivité croisée (Details): Mouse (96 %), Xenopus laevis (88 %), Bovine (97 %), Xenopus tropicalis (90 %)

Attributs du produit: Rabbit Polyclonal antibody to STAM (signal transducing adaptor molecule (SH3 domain and ITAM motif) 1)
STAM antibody

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human STAM. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

Commentaires:

Positive Control: 293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur STAM

Antigène: STAM (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 1 (STAM))

Autre désignation: STAM (STAM Produits)

Synonymes: anticorps STAM-1, anticorps STAM1, anticorps wu:fv75b10, anticorps zgc:55725, anticorps RGD1564499, anticorps signal transducing adaptor molecule, anticorps signal transducing adapter molecule 1, anticorps Signal transducing adapter molecule 1, anticorps signal transducing adaptor molecule (SH3 domain and ITAM motif) 1, anticorps STAM, anticorps CpipJ_CPIJ003516, anticorps Tsp_03939, anticorps stam-1, anticorps Stam, anticorps stam

Sujet: This gene was identified by the rapid tyrosine-phosphorylation of its product in response to cytokine stimulation. The encoded protein contains a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM). This protein associates with JAK3 and JAK2 kinases via its ITAM region, and is phosphorylated by the JAK kinases upon cytokine stimulation, which suggests the function of this protein is as an adaptor molecule involved in the downstream signaling of cytokine receptors. HGS/HRS (hepatocyte grwoth factor-regulated tyrosine kinase substrate) has been found to bind and counteract the function of this protein.

Cellular Localization: Cytoplasm (Probable) , Early endosome membrane, Peripheral membrane protein, Cytoplasmic side

Poids moléculaire: 59 kDa

ID gène: 8027

Pathways: EGFR Signaling Pathway, EGFR Downregulation