WNT11 anticorps (Center)

N° du produit ABIN2856232

Détail du produit anti-WNT11 anticorps

Antigène: WNT11 (Wingless-Type MMTV Integration Site Family, Member 11 (WNT11))

Épitope: Center

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WNT11 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Réactivité croisée: Poulet, Rat (Rattus), Xenopus laevis, Boeuf (Vache)

Réactivité croisée (Details): Chicken (85 %), Rat (96 %), Xenopus laevis (81 %), Bovine (98 %)

Attributs du produit: Rabbit Polyclonal antibody to WNT11 (wingless-type MMTV integration site family, member 11)
WNT11 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human WNT11. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: Suggested dilution Reference ICC/IF 1:100-1:1000* Immunohistochemistry Assay-dependent dilution IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* ImmunohistochemistryAssay-dependent dilution IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

Commentaires:

Positive Control: 293T , A431 , HeLa , HepG2 , mouse heart

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS, 20 % Glycerol ( pH 7). 0.025 % ProClin 300 was added as a preservative.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Références pour anticorps anti-WNT11 (ABIN2856232)

Glaeser, Urban, Fenech, Voloshanenko, Kranz, Lari, Christianson, Boutros: "ERAD-dependent control of the Wnt secretory factor Evi." dans: The EMBO journal, Vol. 37, Issue 4, (2018) (PubMed).

Jain, Noordam, Hoshi, Vallania, Conrad: "Validating single-cell genomics for the study of renal development." dans: Kidney international, Vol. 86, Issue 5, pp. 1049-55, (2015) (PubMed).

Détails sur WNT11

Antigène: WNT11 (Wingless-Type MMTV Integration Site Family, Member 11 (WNT11))

Autre désignation: WNT11 (WNT11 Produits)

Synonymes: anticorps HWNT11, anticorps Wnt11r, anticorps Xwnt11, anticorps Xwnt-11, anticorps wnt11-r, anticorps XWnt-11, anticorps wnt11b, anticorps wnt11b-2, anticorps Slb/Wnt11, anticorps cb748, anticorps slb, anticorps Wnt12, anticorps WNT11, anticorps wnt-11, anticorps xwnt11, anticorps Wnt family member 11, anticorps wingless-type MMTV integration site family member 11 L homeolog, anticorps wingless-type MMTV integration site family, member 11B, anticorps wingless-type MMTV integration site family, member 11, anticorps protein Wnt-11-like, anticorps wingless-type MMTV integration site family, member 10B, anticorps wingless-type MMTV integration site family, member 11B L homeolog, anticorps WNT11, anticorps Wnt11, anticorps wnt11.L, anticorps wnt11b, anticorps wnt11, anticorps LOC100229189, anticorps Wnt10b, anticorps wnt11b.L

Sujet: The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 97 % , 85 %, and 63 % amino acid identity with mouse, chicken, and Xenopus Wnt11 protein, respectively. This gene may play roles in the development of skeleton, kidney and lung, and is considered to be a plausible candidate gene for High Bone Mass Syndrome.

Cellular Localization: Secreted , extracellular space , extracellular matrix

Poids moléculaire: 39 kDa

ID gène: 7481

Pathways: Signalisation WNT, Cell-Cell Junction Organization