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DENND1B anticorps (Center)

DENND1B Reactivité: Humain, Souris WB, ICC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2856495
  • Antigène Voir toutes DENND1B Anticorps
    DENND1B (DENN/MADD Domain Containing 1B (DENND1B))
    Épitope
    • 15
    • 9
    • 8
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    Reactivité
    • 31
    • 19
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 45
    • 1
    Lapin
    Clonalité
    • 46
    Polyclonal
    Conjugué
    • 15
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp DENND1B est non-conjugé
    Application
    • 39
    • 16
    • 15
    • 14
    • 13
    • 13
    • 8
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Attributs du produit
    Rabbit Polyclonal antibody to DENND1B (DENN/MADD domain containing 1B)
    DENND1B antibody [N1C1]
    Purification
    Purified by antigen-affinity chromatography.
    Immunogène
    Recombinant protein encompassing a sequence within the center region of human DENND1B. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product DENND1B Anticorps primaire
  • Indications d'application
    Suggested dilution Reference ICC/IF 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* Western blot1:500-1:3000*
    Commentaires

    Positive Control: 293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji , mouse brain

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.9 mg/mL
    Buffer
    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    Agent conservateur
    Thimerosal (Merthiolate)
    Précaution d'utilisation
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Antigène
    DENND1B (DENN/MADD Domain Containing 1B (DENND1B))
    Autre désignation
    DENND1B (DENND1B Produits)
    Synonymes
    anticorps C1ORF18, anticorps C1orf218, anticorps FAM31B, anticorps 4632404N19Rik, anticorps 4930467M19Rik, anticorps 6820401H01Rik, anticorps F730008N07Rik, anticorps Fam31b, anticorps si:ch211-195i21.1, anticorps DENN domain containing 1B, anticorps DENN/MADD domain containing 1B, anticorps DENND1B, anticorps dennd1b, anticorps Dennd1b
    Sujet
    Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1B, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2, see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson, 2010 [PubMed 20154091]).[supplied by OMIM]

    Poids moléculaire
    48 kDa
    ID gène
    163486
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