WNT10A anticorps (Center)

N° du produit ABIN2856795

Détail du produit anti-WNT10A anticorps

Antigène: WNT10A (Wingless-Type MMTV Integration Site Family, Member 10A (WNT10A))

Épitope: Center

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WNT10A est non-conjugé

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Réactivité croisée: Souris, Rat (Rattus), Boeuf (Vache)

Réactivité croisée (Details): Mouse (96 %), Rat (97 %), Bovine (96 %)

Attributs du produit: Rabbit polyclonal antibody to WNT10A (wingless-type MMTV integration site family, member 10A)
WNT10A antibody [N1C1-2]

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human WNT10A. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: Suggested dilution Reference ICC/IF 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* Western blot1:500-1:3000*

Commentaires:

Positive Control: Molt-4 , Raji

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur WNT10A

Antigène: WNT10A (Wingless-Type MMTV Integration Site Family, Member 10A (WNT10A))

Autre désignation: WNT10A (WNT10A Produits)

Sujet: The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is strongly expressed in the cell lines of promyelocytic leukemia and Burkitt's lymphoma. In addition, it and another family member, the WNT6 gene, are strongly coexpressed in colorectal cancer cell lines. The gene overexpression may play key roles in carcinogenesis through activation of the WNT-beta-catenin-TCF signaling pathway. This gene and the WNT6 gene are clustered in the chromosome 2q35 region.

Cellular Localization: Secreted , extracellular space , extracellular matrix

Poids moléculaire: 46 kDa

ID gène: 80326

Pathways: Signalisation WNT