SLC22A9 anticorps

N° du produit ABIN289969

Détail du produit anti-SLC22A9 anticorps

Antigène: SLC22A9 (Solute Carrier Family 22 (Organic Anion Transporter), Member 9 (SLC22A9))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLC22A9 est non-conjugé

Application: Immunohistochemistry (IHC)

Purification: This antibody was purified from rabbit serum immunized with synthesized C-end peptide of human OAT4 by peptide affinity chromatography.

Immunogène: Partial peptide of Human Organic Anion Transporter 4 (OAT4)

Information d'application

Indications d'application: Working dilution for immunohistochemistry: 1-5ug/ml

Restrictions: For Research Use only

Stockage

Concentration: 0.1 mg/ml

Buffer: PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)

Agent conservateur: ProClin

Stock: -20 °C

Détails sur SLC22A9

Antigène: SLC22A9 (Solute Carrier Family 22 (Organic Anion Transporter), Member 9 (SLC22A9))

Autre désignation: Organic Anion Transporter 4 (OAT4) (SLC22A9 Produits)

Synonymes: anticorps HOAT4, anticorps OAT4, anticorps OAT7, anticorps UST3H, anticorps ust3, anticorps SLC22A25, anticorps solute carrier family 22 member 9, anticorps solute carrier family 22 (organic anion transporter), member 9, anticorps SLC22A9

Sujet: To eliminate the drug, xenobiotics, a varirety of endogeneous substances, and their metabolites out of thebody, specific membrane proteins named transporters are required. There are two major pathways for theelimination, one of which is hepatic one through bile, and another is renal one to urine. The transporter fallinto various transport systems by the transportative substrate. In particular, oraganic ion transporter familyis comprised of organic anion transport family (OAT), oraganic cation transport family (OCT),OCTN/carnitine transport family, and OAT are multispecific organic anion transpoters, the substrates ofwhich include a lot of both endogeneous and exogeneous anions.Human organic anion transporter 4 (OAT4) encodes a 550 amino acid residue protein, and is predicted 12putative membrane-spanning protein. OAT4 mediates the high-affinity Na+-independent transport ofesteron sulfate, dehydroepiandrosterone (DHEA) sulfate, and ochratoxin A, p-aminohippurate (PAH).OAT4 is expressed in the kidney and placenta. OAT4 might be responsible for the elimination anddetoxification of harmful anionic sybstances from the fetus.This antidody has been proved to be useful for immunohistochemistry .