Lamin B1 anticorps (AA 397-586)

N° du produit ABIN3015698

Détail du produit anti-Lamin B1 anticorps

Antigène: Lamin B1 (LMNB1)

Épitope: AA 397-586

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Lamin B1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Séquence: RVTVSRASSS RSVRTTRGKR KRVDVEESEA SSSVSISHSA SATGNVCIEE IDVDGKFIRL KNTSEQDQPM GGWEMIRKIG DTSVSYKYTS RYVLKAGQTV TIWAANAGVT ASPPTDLIWK NQNSWGTGED VKVILKNSQG EEVAQRSTVF KTTIPEEEEE EEEAAGVVVE EELFHQQGTP RASNRSCAIM

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 397-586 of human Lamin B1 (NP_005564.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-Lamin B1 (ABIN3015698)

Cheng, Wei, Xie, Peng, Yan, Qin, Liu, Xu, Li, Zhang: "Alleviation of Toxicity Caused by Overactivation of Pparα through Pparα-Inducible miR-181a2." dans: Molecular therapy. Nucleic acids, Vol. 9, pp. 195-206, (2017) (PubMed).

Ma, Fang, Luo, Yang, Wang, Zhang, Wang, Chen, Chan, Liu: "The C-ETS2-TFEB Axis Promotes Neuron Survival under Oxidative Stress by Regulating Lysosome Activity." dans: Oxidative medicine and cellular longevity, Vol. 2016, pp. 4693703, (2017) (PubMed).

Détails sur Lamin B1

Antigène: Lamin B1 (LMNB1)

Autre désignation: LMNB1 (LMNB1 Produits)

Synonymes: anticorps MGC52550, anticorps Lamin-L(I), anticorps lamin-b, anticorps lmn, anticorps lmn2, anticorps lmnb, anticorps LMNB1, anticorps ADLD, anticorps LMN, anticorps LMN2, anticorps LMNB, anticorps fc06g01, anticorps wu:fc06g01, anticorps lamin B1 L homeolog, anticorps lamin B1, anticorps lmnb1.L, anticorps lmnb1, anticorps LMNB1, anticorps Lmnb1

Sujet: This gene encodes one of the two B-type lamin proteins and is a component of the nuclear lamina. A duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD). Alternative splicing results in multiple transcript variants.,ADLD,LMN,LMN2,LMNB,Lamin B1,LMNB1,lamin-B1,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Cytoskeleton,Intermediate Filaments,LMNB1

Poids moléculaire: 66 kDa

ID gène: 4001

UniProt: P20700

Pathways: Apoptose, Caspase Cascade in Apoptosis