Importin 5 anticorps (AA 20-300)

N° du produit ABIN3015798

Détail du produit anti-Importin 5 anticorps

Antigène: Importin 5 (IPO5)

Épitope: AA 20-300

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Importin 5 est non-conjugé

Application: Western Blotting (WB)

Séquence: AAAAAEQQQF YLLLGNLLSP DNVVRKQAEE TYENIPGQSK ITFLLQAIRN TTAAEEARQM AAVLLRRLLS SAFDEVYPAL PSDVQTAIKS ELLMIIQMET QSSMRKKVCD IAAELARNLI DEDGNNQWPE GLKFLFDSVS SQNVGLREAA LHIFWNFPGI FGNQQQHYLD VIKRMLVQCM QDQEHPSIRT LSARATAAFI LANEHNVALF KHFADLLPGF LQAVNDSCYQ NDDSVLKSLV EIADTVPKYL RPHLEATLQL SLKLCGDTSL NNMQRQLALE V

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 20-300 of human IPO5 (NP_002262.3).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Importin 5

Antigène: Importin 5 (IPO5)

Autre désignation: IPO5 (IPO5 Produits)

Synonymes: anticorps IPO5, anticorps RANBP5, anticorps IMB3, anticorps KPNB3, anticorps Pse1, anticorps imp5, anticorps 1110011C18Rik, anticorps 5730478E03Rik, anticorps AA409333, anticorps C76941, anticorps Kpnb3, anticorps Ranbp5, anticorps importin 5, anticorps IPO5, anticorps Ipo5

Sujet: Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family.,IPO5,IMB3,KPNB3,Pse1,RANBP5,imp5,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Signal Transduction,IPO5

Poids moléculaire: 116 kDa/123 kDa/125 kDa

ID gène: 3843

UniProt: O00410

Pathways: Protein targeting to Nucleus