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CNTF Receptor alpha anticorps (AA 190-340)

CNTFR Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3016492
  • Antigène Voir toutes CNTF Receptor alpha (CNTFR) Anticorps
    CNTF Receptor alpha (CNTFR) (Ciliary Neurotrophic Factor Receptor (CNTFR))
    Épitope
    • 15
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 190-340
    Reactivité
    • 34
    • 29
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 42
    • 2
    • 1
    Lapin
    Clonalité
    • 44
    • 1
    Polyclonal
    Conjugué
    • 14
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CNTF Receptor alpha est non-conjugé
    Application
    • 28
    • 14
    • 14
    • 13
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Séquence
    NATAITFDEF TIVKPDPPEN VVARPVPSNP RRLEVTWQTP STWPDPESFP LKFFLRYRPL ILDQWQHVEL SDGTAHTITD AYAGKEYIIQ VAAKDNEIGT WSDWSVAAHA TPWTEEPRHL TTEAQAAETT TSTTSSLAPP PTTKICDPGE L
     Réactivité croisée
    Humain, Souris, Rat
    Attributs du produit
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogène
    Recombinant fusion protein containing a sequence corresponding to amino acids 190-340 of human CNTFR (NP_001833.1).
    Isotype
    IgG
    Top Product
    Discover our top product CNTFR Anticorps primaire
  • Indications d'application
    WB,1:400 - 1:2000
    Restrictions
    For Research Use only
  • Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Yong, Groeger, von Bremen, Ruf: "Ciliary Neurotrophic Factor (CNTF) and Its Receptors Signal Regulate Cementoblasts Apoptosis through a Mechanism of ERK1/2 and Caspases Signaling." dans: International journal of molecular sciences, Vol. 23, Issue 15, (2022) (PubMed).

  • Antigène
    CNTF Receptor alpha (CNTFR) (Ciliary Neurotrophic Factor Receptor (CNTFR))
    Autre désignation
    CNTFR (CNTFR Produits)
    Synonymes
    anticorps CNTFR-alpha, anticorps CNTFRALPHA, anticorps Cntfralpha, anticorps cb549, anticorps fj33e02, anticorps sb:cb549, anticorps wu:fj33e02, anticorps si:bz76a6.1, anticorps si:dz248f2.1, anticorps si:rp71-76a6.1, anticorps ciliary neurotrophic factor receptor, anticorps ciliary neurotrophic factor receptor L homeolog, anticorps CNTFR, anticorps cntfr.L, anticorps Cntfr, anticorps cntfr
    Sujet
    This gene encodes a member of the type 1 cytokine receptor family. The encoded protein is the ligand-specific component of a tripartite receptor for ciliary neurotrophic factor, which plays a critical role in neuronal cell survival, differentiation and gene expression. Binding of ciliary neurotrophic factor to the encoded protein recruits the transmembrane components of the receptor, gp130 and leukemia inhibitory factor receptor, facilitating signal transduction. Single nucleotide polymorphisms in this gene may be associated with variations in muscle strength, as well as early onset of eating disorders. Alternatively spliced transcript variants have been observed for this gene.,CNTFR,Signal Transduction,Neuroscience,CNTFR
    Poids moléculaire
    40 kDa
    ID gène
    1271
    UniProt
    P26992
    Pathways
    Signalistation JAK/STAT, Feeding Behaviour
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