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TERT anticorps (C-Term)

TERT Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3017112
  • Antigène Voir toutes TERT Anticorps
    TERT (Telomerase Reverse Transcriptase (TERT))
    Épitope
    • 16
    • 16
    • 10
    • 10
    • 7
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 106
    • 38
    • 20
    • 5
    • 1
    • 1
    Humain
    Hôte
    • 108
    • 6
    • 1
    Lapin
    Clonalité
    • 99
    • 16
    Polyclonal
    Conjugué
    • 60
    • 8
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp TERT est non-conjugé
    Application
    • 75
    • 55
    • 39
    • 27
    • 17
    • 16
    • 16
    • 13
    • 7
    • 7
    • 6
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    NIYKILLLQA YRFHACVLQL PFHQQVWKNP TFFLRVISDT ASLCYSILKA KNAGMSLGAK GAAGPLPSEA VQWLCHQAFL LKLTRHRVTY VPLLGSLRTA QTQLSRKLPG TTLTALEAAA NPALPSDFKT ILD
     Réactivité croisée
    Humain, Rat
    Attributs du produit
    Polyclonal Antibodies
    Immunogène
    A synthetic peptide corresponding to a sequence within amino acids 1000 to the C-terminus of human TERT (NP_937983.2).
    Isotype
    IgG
    Top Product
    Discover our top product TERT Anticorps primaire
  • Indications d'application
    WB,1:500 - 1:2000
    Restrictions
    For Research Use only
  • Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    TERT (Telomerase Reverse Transcriptase (TERT))
    Autre désignation
    TERT (TERT Produits)
    Synonymes
    anticorps CMM9, anticorps DKCA2, anticorps DKCB4, anticorps EST2, anticorps PFBMFT1, anticorps TCS1, anticorps TP2, anticorps TRT, anticorps hEST2, anticorps hTRT, anticorps chTERT, anticorps Tert, anticorps ATTERT, anticorps F5E19.190, anticorps F5E19_190, anticorps telomerase reverse transcriptase, anticorps tert, anticorps TR, anticorps est2, anticorps tcs1, anticorps telomerase, anticorps tert-A, anticorps tp2, anticorps trt, anticorps xTERT, anticorps telomerase reverse transcriptase, anticorps Telomerase Reverse Transcriptase, anticorps Tertp, anticorps Telomerase catalytic subunit, anticorps telomerase reverse transcriptase L homeolog, anticorps TERT, anticorps trt-1, anticorps Tert, anticorps tert, anticorps CMU_003490, anticorps VDBG_04487, anticorps GL50803_16225, anticorps tert.L
    Sujet
    Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, encoded by this gene, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks. Alternatively spliced variants encoding different isoforms of telomerase reverse transcriptase have been identified, the full-length sequence of some variants has not been determined. Alternative splicing at this locus is thought to be one mechanism of regulation of telomerase activity.,TERT,CMM9,DKCA2,DKCB4,EST2,PFBMFT1,TCS1,TP2,TRT,hEST2,hTRT,Epigenetics & Nuclear Signaling,Cancer,Tumor biomarkers,Cell Biology & Developmental Biology,Stem Cells,Embryonic Stem Cells,TERT
    Poids moléculaire
    88 kDa/90 kDa/120 kDa/126 kDa
    ID gène
    7015
    UniProt
    O14746
    Pathways
    Telomere Maintenance
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