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ABCC5 anticorps (AA 1-179)

ABCC5 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3017214
  • Antigène Voir toutes ABCC5 Anticorps
    ABCC5 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 5 (ABCC5))
    Épitope
    • 15
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-179
    Reactivité
    • 32
    • 20
    • 13
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 41
    • 3
    • 3
    • 1
    Lapin
    Clonalité
    • 42
    • 6
    Polyclonal
    Conjugué
    • 18
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ABCC5 est non-conjugé
    Application
    • 33
    • 19
    • 13
    • 13
    • 7
    • 5
    • 5
    • 3
    • 3
    • 2
    Western Blotting (WB)
    Séquence
    MKDIDIGKEY IIPSPGYRSV RERTSTSGTH RDREDSKFRR TRPLECQDAL ETAARAEGLS LDASMHSQLR ILDEEHPKGK YHHGLSALKP IRTTSKHQHP VDNAGLFSCM TFSWLSSLAR VAHKKGELSM EDVWSLSKHE SSDVNCRRLE RLWQEELNEV GPDAASLRRV VWIFCRTRL
     Réactivité croisée
    Humain, Souris, Rat
    Attributs du produit
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogène
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-179 of human ABCC5 (NP_005679.2).
    Isotype
    IgG
    Top Product
    Discover our top product ABCC5 Anticorps primaire
  • Indications d'application
    WB,1:1000 - 1:2000
    Restrictions
    For Research Use only
  • Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    ABCC5 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 5 (ABCC5))
    Autre désignation
    ABCC5 (ABCC5 Produits)
    Synonymes
    anticorps ABC33, anticorps EST277145, anticorps MOAT-C, anticorps MOATC, anticorps MRP5, anticorps SMRP, anticorps pABC11, anticorps 2900011L11Rik, anticorps AI132311, anticorps Abcc5a, anticorps Abcc5b, anticorps Mrp5, anticorps abc33, anticorps abcc5, anticorps moat-c, anticorps moatc, anticorps mrp5, anticorps pabc11, anticorps smrp, anticorps ATP binding cassette subfamily C member 5, anticorps ATP-binding cassette, sub-family C (CFTR/MRP), member 5, anticorps ATP binding cassette subfamily C member 5 L homeolog, anticorps ABCC5, anticorps Abcc5, anticorps abcc5.L
    Sujet
    The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions in the cellular export of its substrate, cyclic nucleotides. This export contributes to the degradation of phosphodiesterases and possibly an elimination pathway for cyclic nucleotides. Studies show that this protein provides resistance to thiopurine anticancer drugs, 6-mercatopurine and thioguanine, and the anti-HIV drug 9-(2-phosphonylmethoxyethyl)adenine. This protein may be involved in resistance to thiopurines in acute lymphoblastic leukemia and antiretroviral nucleoside analogs in HIV-infected patients. Alternative splicing results in multiple transcript variants.,ABCC5,ABC33,EST277145,MOAT-C,MOATC,MRP5,SMRP,pABC11,Cancer,Signal Transduction,Endocrine & Metabolism,ABCC5
    Poids moléculaire
    23 kDa/25 kDa/155 kDa/160 kDa
    ID gène
    10057
    UniProt
    O15440
    Pathways
    Glycosaminoglycan Metabolic Process
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