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Cyclin E1 anticorps (pThr395)

CCNE1 Reactivité: Humain WB, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3019435
  • Antigène Voir toutes Cyclin E1 (CCNE1) Anticorps
    Cyclin E1 (CCNE1)
    Épitope
    • 28
    • 16
    • 15
    • 13
    • 9
    • 8
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr395
    Reactivité
    • 150
    • 38
    • 34
    • 3
    • 2
    • 2
    • 2
    Humain
    Hôte
    • 125
    • 24
    • 1
    Lapin
    Clonalité
    • 114
    • 36
    Polyclonal
    Conjugué
    • 85
    • 8
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp Cyclin E1 est non-conjugé
    Application
    • 106
    • 49
    • 48
    • 42
    • 36
    • 28
    • 22
    • 13
    • 13
    • 10
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Séquence
    LLTPP
     Réactivité croisée
    Humain, Souris, Rat
    Attributs du produit
    Phosphorylated Antibodies
    Purification
    Affinity purification
    Immunogène
    A synthetic phosphorylated peptide around T395 of human Cyclin E1 (NP_001229.1).
    Isotype
    IgG
    Top Product
    Discover our top product CCNE1 Anticorps primaire
  • Indications d'application
    WB,1:500 - 1:2000,IF,1:50 - 1:100
    Restrictions
    For Research Use only
  • Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    Cyclin E1 (CCNE1)
    Autre désignation
    CCNE1 (CCNE1 Produits)
    Synonymes
    anticorps CCNE1, anticorps ccne, anticorps cyclinE, anticorps CCNE, anticorps AW538188, anticorps CycE1, anticorps CYCLE, anticorps Ccne, anticorps cyce2, anticorps cycE3, anticorps cyce, anticorps fa18e07, anticorps wu:fa18e07, anticorps cyclin E1, anticorps cyclin E1 L homeolog, anticorps cyclin E1 S homeolog, anticorps CCNE1, anticorps ccne1, anticorps Ccne1, anticorps ccne1.L, anticorps ccne1.S
    Sujet
    The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition. This protein accumulates at the G1-S phase boundary and is degraded as cells progress through S phase. Overexpression of this gene has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumorigenesis. This protein was found to associate with, and be involved in, the phosphorylation of NPAT protein (nuclear protein mapped to the ATM locus), which participates in cell-cycle regulated histone gene expression and plays a critical role in promoting cell-cycle progression in the absence of pRB.,CCNE1,CCNE,pCCNE1,cyclin E1,Epigenetics & Nuclear Signaling,Cancer,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Cyclins,G1/S Checkpoint,Hedgehog Signaling Pathway,Protein phosphorylation,CCNE1
    Poids moléculaire
    41 kDa/45 kDa/47 kDa
    ID gène
    898
    UniProt
    P24864
    Pathways
    Cycle Cellulaire, Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Mitotic G1-G1/S Phases
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