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eIF4EBP1 anticorps (pThr37, pThr46)

EIF4EBP1 Reactivité: Humain WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3019470
  • Antigène Voir toutes eIF4EBP1 (EIF4EBP1) Anticorps
    eIF4EBP1 (EIF4EBP1) (Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))
    Épitope
    • 29
    • 29
    • 28
    • 21
    • 16
    • 15
    • 12
    • 11
    • 11
    • 9
    • 8
    • 7
    • 7
    • 6
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    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr37, pThr46
    Reactivité
    • 243
    • 168
    • 124
    • 21
    • 14
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 256
    • 19
    • 4
    Lapin
    Clonalité
    • 237
    • 44
    Polyclonal
    Conjugué
    • 116
    • 25
    • 18
    • 12
    • 12
    • 11
    • 10
    • 9
    • 9
    • 9
    • 9
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp eIF4EBP1 est non-conjugé
    Application
    • 217
    • 90
    • 87
    • 67
    • 66
    • 46
    • 30
    • 23
    • 16
    • 12
    • 10
    • 8
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
     Réactivité croisée
    Humain, Souris, Rat
    Attributs du produit
    Phosphorylated Antibodies
    Purification
    Affinity purification
    Immunogène
    A phospho specific peptide corresponding to residues surrounding T37/46 of human Phospho-eIF4EBP1-T37/46
    Isotype
    IgG
    Top Product
    Discover our top product EIF4EBP1 Anticorps primaire
  • Indications d'application
    WB,1:500 - 1:2000,IHC,1:50 - 1:200
    Restrictions
    For Research Use only
  • Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Zhou, Liu, Xue, Zheng, Liu, Ma, Li, Liu et al.: "Combination of Endothelial-Monocyte-Activating Polypeptide-II with Temozolomide Suppress Malignant Biological Behaviors of Human Glioblastoma Stem Cells via miR-590-3p/MACC1 Inhibiting PI3K/AKT/mTOR ..." dans: Frontiers in molecular neuroscience, Vol. 10, pp. 68, (2017) (PubMed).

    Guo, Hu, Chen, Li, Ye, Cheng, Zhang, He: "iTRAQ-based comparative proteomic analysis of Vero cells infected with virulent and CV777 vaccine strain-like strains of porcine epidemic diarrhea virus." dans: Journal of proteomics, Vol. 130, pp. 65-75, (2016) (PubMed).

  • Antigène
    eIF4EBP1 (EIF4EBP1) (Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))
    Autre désignation
    EIF4EBP1 (EIF4EBP1 Produits)
    Synonymes
    anticorps 4E-BP1, anticorps 4EBP1, anticorps BP-1, anticorps PHAS-I, anticorps 4e-bp1, anticorps AA959816, anticorps 153432_at, anticorps 43-BP, anticorps 4E-BP, anticorps 4EBP, anticorps 4e-bp, anticorps 4eBP, anticorps 4ebp, anticorps BcDNA.HL08053, anticorps BcDNA:HL08053, anticorps CG8846, anticorps CT8705, anticorps Dm 4E-BP, anticorps Dmel\\CG8846, anticorps Phas1, anticorps Thor/EIF4EBP, anticorps anon-WO0172774.158, anticorps d4E-BP, anticorps d4E-BP1, anticorps d4EBP, anticorps d4e-bp, anticorps d4eBP, anticorps dthor, anticorps eIF4E-BP, anticorps l(2)06270, anticorps l(2)k07736, anticorps l(2)k13517, anticorps pp20, anticorps thor, anticorps EIF4EBP1, anticorps fc04h09, anticorps wu:fc04h09, anticorps zgc:64137, anticorps eukaryotic translation initiation factor 4E binding protein 1, anticorps CG8846 gene product from transcript CG8846-RA, anticorps EIF4EBP1, anticorps Eif4ebp1, anticorps Thor, anticorps eif4ebp1
    Sujet
    This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.,4E-BP1,4EBP1,BP-1,PHAS-I,EIF4EBP1,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Signal Transduction,PI3K-Akt Signaling Pathway,mTOR Signaling Pathway,Endocrine & Metabolism,AMPK Signaling Pathway,Insulin Receptor Signaling Pathway,Endocrine and metabolic diseases,Diabetes,Metabolic disorders,Obesity,Cardiovascular,Angiogenesis,Akt downstream targets,Protein phosphorylation,EIF4EBP1
    Poids moléculaire
    12 kDa
    ID gène
    1978
    UniProt
    Q13541
    Pathways
    Signalisation MAPK, Signalisation PI3K-Akt, Signalisation RTK, AMPK Signaling, Regulation of Cell Size, BCR Signaling
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