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STAT5A anticorps (pTyr694)

STAT5A Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3019614
  • Antigène Voir toutes STAT5A Anticorps
    STAT5A (Signal Transducer and Activator of Transcription 5A (STAT5A))
    Épitope
    • 56
    • 24
    • 17
    • 15
    • 15
    • 14
    • 9
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr694
    Reactivité
    • 205
    • 110
    • 83
    • 25
    • 14
    • 9
    • 9
    • 6
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 178
    • 30
    • 2
    Lapin
    Clonalité
    • 158
    • 52
    Polyclonal
    Conjugué
    • 119
    • 10
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp STAT5A est non-conjugé
    Application
    • 163
    • 69
    • 59
    • 40
    • 39
    • 30
    • 24
    • 23
    • 21
    • 13
    • 10
    • 8
    • 8
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    DGYVK
     Réactivité croisée
    Humain
    Attributs du produit
    Phosphorylated Antibodies
    Immunogène
    A synthetic phosphorylated peptide around Y694 of human STAT5A (NP_001275647.1).
    Isotype
    IgG
    Top Product
    Discover our top product STAT5A Anticorps primaire
  • Indications d'application
    WB,1:500 - 1:2000
    Restrictions
    For Research Use only
  • Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Shen, Li, You, Wu, Wu, Zhao, Zhu, Guo, Li, Li, Ma, Yang, Chen: "Oral exposure to diisodecyl phthalate aggravates allergic dermatitis by oxidative stress and enhancement of thymic stromal lymphopoietin." dans: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, Vol. 99, pp. 60-69, (2017) (PubMed).

  • Antigène
    STAT5A (Signal Transducer and Activator of Transcription 5A (STAT5A))
    Autre désignation
    STAT5A (STAT5A Produits)
    Synonymes
    anticorps MGF, anticorps STAT5, anticorps AA959963, anticorps Stat5, anticorps STAT5A/MGF, anticorps STATA5, anticorps STAT5A, anticorps stat5, anticorps stat5b, anticorps signal transducer and activator of transcription 5A, anticorps signal transducer and activator of transcription 5a, anticorps STAT5A, anticorps Stat5a, anticorps stat5a, anticorps LOC100348518, anticorps LOC100716811
    Sujet
    The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. Alternatively spliced transcript variants have been found for this gene.,MGF,STAT5,STAT5A,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Immunology & Inflammation,IL-6 Receptor Signaling Pathway,Stem Cells,Protein phosphorylation,STAT5A
    Poids moléculaire
    86 kDa/90 kDa
    ID gène
    6776
    UniProt
    P42229
    Pathways
    Signalistation JAK/STAT, Signalisation RTK, Response to Growth Hormone Stimulus, C21-Steroid Hormone Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Activated T Cell Proliferation
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