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PRKCA/PRKCB (pThr638), (pThr641) anticorps

Reactivité: Humain IF, IHC, WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3019761
  • Antigène
    PRKCA/PRKCB
    Épitope
    pThr638, pThr641
    Reactivité
    Humain
    Hôte
    Lapin
    Clonalité
    Polyclonal
    Application
    Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
     Réactivité croisée
    Humain, Souris, Rat
    Attributs du produit
    Phosphorylated Antibodies
    Purification
    Affinity purification
    Immunogène
    A phospho specific peptide corresponding to residues surrounding T638/641 of human PKCalpha/beta II
    Isotype
    IgG
  • Indications d'application
    WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:100 - 1:200
    Restrictions
    For Research Use only
  • Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    PRKCA/PRKCB
    Sujet
    Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported.,PKC-beta,PKCB,PRKCB1,PRKCB2,Protein phosphorylation,Protein phosphorylation,Protein phosphorylation,PRKCA/PRKCB
    Poids moléculaire
    76 kDa/77 kDa
    ID gène
    5578, 5579
    UniProt
    P17252, P05771
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