Souris anti-Humain IgG (Fc Region) Anticorps (HRP)

Détails pour le produit réf. ABIN302063, Fournisseur: Connectez-vous pour afficher
Antigène
Épitope
Fc Region
4782
2534
1960
1067
1022
861
306
292
35
34
31
8
7
7
3
3
2
2
1
1
1
1
1
Reactivité
Humain
2896
2761
2297
1676
1453
790
626
454
395
387
359
346
298
296
221
138
135
130
41
31
29
24
16
11
10
8
7
6
5
5
4
4
4
3
3
3
3
3
3
3
2
2
1
1
1
1
1
Hôte
Souris
6786
4909
1788
922
609
392
91
68
55
18
8
5
5
5
2
1
1
Clonalité (Clone)
Monoclonal ()
Conjugué
HRP
2267
1903
1785
1360
769
686
531
294
268
227
226
201
158
141
129
110
79
75
69
55
52
48
48
45
40
39
37
35
35
29
28
28
27
27
27
27
27
27
22
19
19
19
19
17
15
15
15
15
15
15
14
12
12
11
10
10
10
9
9
9
9
9
8
8
8
8
6
6
6
6
6
5
5
5
4
4
4
4
4
4
4
4
4
4
4
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Application
ELISA, Western Blotting (WB)
Options
Fournisseur
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Supplier Product No.
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Immunogène Fusion protein of human IgG Fc fragment.
Clone EM-07
Isotype IgG1
Specificité The antibody EM-07 reacts with Fc part of human IgG heavy chain and with isolated Fc fragments.
Attributs du produit The purified antibody is conjugated with Horseradish Peroxidase (HRP) of high specific activity and RZ=3.
Sujet Immunoglobulin G (IgG) is a 150 kDa soluble protein that serves as a major effector molecule of the humoral immune response in man. Its concentration in blood plasma of healthy individuals is approximately 10 g/l, which accounts for about 75 % of the total plasma immunoglobulins. IgG has the highest stability of blood immunoglobulins (T1/2 = 21 days) and is able of placental transfer. IgG is secreted by plasma cells at a comparably high rate as other immunoglobulins.
Poids moléculaire 150 kDa
Indications d'application The peroxidase conjugate is designed for ELISA and Western Blotting. Suggested working dilution for ELISA is 0.1 - 0.5 µg/mL. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.

Working concentrations should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer The reagent is provided in phosphate buffered saline (PBS) containing 0.01 % (w/v) thimerosal and 1 % (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent.
Agent conservateur Thimerosal (Merthiolate)
Précaution d'utilisation Biohazard Informations: This product contains thimerosal which is hazardous.
Conseil sur la manipulation Do not freeze.
Avoid prolonged exposure to light.
Stock 4 °C
Stockage commentaire Store in the dark at 2-8 °C. Do not use after expiration date stamped on vial label. Short-term exposure to room temperature should not affect the quality of the reagent. However, if reagent is stored under any conditions other than those specified, the conditions must be verified by the user.
Supplier Images
Western Blotting (WB) image for Mouse anti-Human IgG (Fc Region) antibody (HRP) (ABIN302063) IgG κ light chain (1), IgG λ light chain (2) and IgG Fc fragment (3) purifi...
Background publications Brinkmann, Heusser: "T cell-dependent differentiation of human B cells into IgM, IgG, IgA, or IgE plasma cells: high rate of antibody production by IgE plasma cells, but limited clonal expansion of IgE precursors." dans: Cellular immunology, Vol. 152, Issue 2, pp. 323-32, 1994 (PubMed).

Balogh, Merétey, Falus, Bozsóky: "Serological abnormalities in juvenile chronic arthritis: a review of 46 cases." dans: Annals of the rheumatic diseases, Vol. 39, Issue 2, pp. 129-34, 1980 (PubMed).

Franklin: "Structure and function of immunoglobulins." dans: Acta endocrinologica. Supplementum, Vol. 194, pp. 77-95, 1975 (PubMed).

Fuller, Keyser: "Serum immunoglobulins after surgical operation." dans: Clinical chemistry, Vol. 21, Issue 6, pp. 667-71, 1975 (PubMed).