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GDF15 anticorps (AA 49-308)

GDF15 Reactivité: Humain WB, IHC, IP, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3020659
  • Antigène Voir toutes GDF15 Anticorps
    GDF15 (Growth Differentiation Factor 15 (GDF15))
    Épitope
    • 18
    • 15
    • 11
    • 8
    • 7
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 49-308
    Reactivité
    • 88
    • 30
    • 23
    • 1
    • 1
    Humain
    Hôte
    • 85
    • 12
    • 3
    • 1
    Lapin
    Clonalité
    • 85
    • 15
    • 1
    Polyclonal
    Conjugué
    • 52
    • 15
    • 9
    • 8
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp GDF15 est non-conjugé
    Application
    • 86
    • 54
    • 35
    • 16
    • 13
    • 13
    • 9
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)
    Séquence
    EDSRFRELRK RYEDLLTRLR ANQSWEDSNT DLVPAPAVRI LTPEVRLGSG GHLHLRISRA ALPEGLPEAS RLHRALFRLS PTASRSWDVT RPLRRQLSLA RPQAPALHLR LSPPPSQSDQ LLAESSSARP QLELHLRPQA ARGRRRARAR NGDHCPLGPG RCCRLHTVRA SLEDLGWADW VLSPREVQVT MCIGACPSQF RAANMHAQIK TSLHRLKPDT VPAPCCVPAS YNPMVLIQKT DTGVSLQTYD DLLAKDCHCI
     Réactivité croisée
    Humain, Souris, Rat
    Attributs du produit
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogène
    Recombinant fusion protein containing a sequence corresponding to amino acids 49-308 of human GDF15 (NP_004855.2).
    Isotype
    IgG
  • Indications d'application
    WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:200,IP,1:50 - 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid freeze / thaw cycles
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Wang, Yang, Dai, Lu, Zhang, Keller: "Prostate cancer promotes a vicious cycle of bone metastasis progression through inducing osteocytes to secrete GDF15 that stimulates prostate cancer growth and invasion." dans: Oncogene, Vol. 38, Issue 23, pp. 4540-4559, (2019) (PubMed).

    Han, Dai, Yousafzai, Wang, Wang, Zhou, Lu, Xu, Feng, Jin, Wang: "CXXC4 activates apoptosis through up-regulating GDF15 in gastric cancer." dans: Oncotarget, Vol. 8, Issue 61, pp. 103557-103567, (2017) (PubMed).

    Tsui, Hsu, Chung, Lin, Feng, Lee, Chang, Juang: "Growth differentiation factor-15: a p53- and demethylation-upregulating gene represses cell proliferation, invasion, and tumorigenesis in bladder carcinoma cells." dans: Scientific reports, Vol. 5, pp. 12870, (2016) (PubMed).

  • Antigène
    GDF15 (Growth Differentiation Factor 15 (GDF15))
    Autre désignation
    GDF15 (GDF15 Produits)
    Synonymes
    anticorps GDF15, anticorps GDF-15, anticorps MIC-1, anticorps MIC1, anticorps NAG-1, anticorps PDF, anticorps PLAB, anticorps PTGFB, anticorps SBF, anticorps growth differentiation factor 15, anticorps GDF15, anticorps Gdf15
    Sujet
    The protein encoded by this gene belongs to the transforming growth factor-beta (TGF-beta) family. The protein is expressed in a broad range of cell types, acts as a pleiotropic cytokine and is involved in the stress reponse program of cells after cellular injury. Increased protein levels are associated with disease states such as tissue hypoxia, inflammation, acute injury and oxidative stress.,GDF15,GDF-15,MIC-1,MIC1,NAG-1,PDF,PLAB,PTGFB,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Cytoskeleton,Extracellular Matrix,Bone,Growth factor,Immunology & Inflammation,Cytokines,Cardiovascular,Heart,Hypertrophy,GDF15
    Poids moléculaire
    34 kDa
    ID gène
    9518
    UniProt
    Q99988
    Pathways
    SARS-CoV-2 Protein Interactome
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