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TUBG1 anticorps (AA 434-449)

TUBG1 Reactivité: Plantes, Protozoa WB, ICC Hôte: Souris Monoclonal TU-32 unconjugated
N° du produit ABIN302067
  • Antigène Voir toutes TUBG1 Anticorps
    TUBG1 (Tubulin, gamma 1 (TUBG1))
    Épitope
    • 13
    • 10
    • 7
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 434-449
    Reactivité
    • 65
    • 31
    • 27
    • 7
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Plantes, Protozoa
    Hôte
    • 48
    • 19
    Souris
    Clonalité
    • 44
    • 23
    Monoclonal
    Conjugué
    • 42
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TUBG1 est non-conjugé
    Application
    • 49
    • 22
    • 12
    • 11
    • 11
    • 9
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunocytochemistry (ICC)
    Specificité
    The antibody TU-32 recognizes C-terminus (amino acids 434-449 in human) of gamma-tubulin, a 48 kDa structural constituent of cytoskeleton and microtubule organizing center (MTOC). The epitope was located in the aminoacid sequence PDYISW (aa441-446 in human), which is identical for gamma-tubulin 1 and gamma-tubulin 2.
    Réactivité croisée (Details)
    Animals, Protozoa, Plants
    Purification
    Purified by protein-A affinity chromatography.
    Pureté
    > 95 % (by SDS-PAGE)
    Immunogène
    human gamma-tubulin peptide EYHAATRPDYISWGTQ, amino acids 434-449
    Clone
    TU-32
    Isotype
    IgG1
    Top Product
    Discover our top product TUBG1 Anticorps primaire
  • Indications d'application
    Western blotting: Recommended dilution: 1-2 μg/mL, reducing conditions.
    Immunocytochemistry: Methanol/acetone fixation required.
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Do not freeze.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C. Do not freeze.
  • Katsetos, Dráberová, Smejkalová, Reddy, Bertrand, de Chadarévian, Legido, Nissanov, Baas, Dráber: "Class III beta-tubulin and gamma-tubulin are co-expressed and form complexes in human glioblastoma cells." dans: Neurochemical research, Vol. 32, Issue 8, pp. 1387-98, (2007) (PubMed).

    Katsetos, Reddy, Dráberová, Smejkalová, Del Valle, Ashraf, Tadevosyan, Yelin, Maraziotis, Mishra, Mörk, Legido, Nissanov, Baas, de Chadarévian, Dráber: "Altered cellular distribution and subcellular sorting of gamma-tubulin in diffuse astrocytic gliomas and human glioblastoma cell lines." dans: Journal of neuropathology and experimental neurology, Vol. 65, Issue 5, pp. 465-77, (2006) (PubMed).

    Sulimenko, Dráberová, Sulimenko, Macurek, Richterová, Dráber, Dráber: "Regulation of microtubule formation in activated mast cells by complexes of gamma-tubulin with Fyn and Syk kinases." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 176, Issue 12, pp. 7243-53, (2006) (PubMed).

    Libusová, Sulimenko, Sulimenko, Hozák, Dráber: "gamma-Tubulin in Leishmania: cell cycle-dependent changes in subcellular localization and heterogeneity of its isoforms." dans: Experimental cell research, Vol. 295, Issue 2, pp. 375-86, (2004) (PubMed).

    Linhartová, Novotná, Sulimenko, Dráberová, Dráber: "Gamma-tubulin in chicken erythrocytes: changes in localization during cell differentiation and characterization of cytoplasmic complexes." dans: Developmental dynamics : an official publication of the American Association of Anatomists, Vol. 223, Issue 2, pp. 229-40, (2002) (PubMed).

    Sulimenko, Sulimenko, Poznanovic, Nechiporuk-Zloy, Böhm, Macurek, Unger, Dráber: "Association of brain gamma-tubulins with alpha beta-tubulin dimers." dans: The Biochemical journal, Vol. 365, Issue Pt 3, pp. 889-95, (2002) (PubMed).

    Dráberová, Mac?rek, Richterová, Böhm, Dráber: "Monoclonal antibody KN-01 against the heavy chain of kinesin." dans: Folia biologica, Vol. 48, Issue 2, pp. 77-9, (2002) (PubMed).

    Nohýnkova, Dráber, Reischig, Kulda: "Localization of gamma-tubulin in interphase and mitotic cells of a unicellular eukaryote, Giardia intestinalis." dans: European journal of cell biology, Vol. 79, Issue 6, pp. 438-45, (2000) (PubMed).

    Binarová, Cenklová, Hause, Kubátová, Lysák, Dolezel, Bögre, Dráber: "Nuclear gamma-tubulin during acentriolar plant mitosis." dans: The Plant cell, Vol. 12, Issue 3, pp. 433-42, (2000) (PubMed).

    Dráberová, Dráberová, Surviladze, Dráber, Dráber: "Protein tyrosine kinase p53/p56(lyn) forms complexes with gamma-tubulin in rat basophilic leukemia cells." dans: International immunology, Vol. 11, Issue 11, pp. 1829-39, (1999) (PubMed).

    Nováková, Dráberová, Schürmann, Czihak, Viklický, Dr-aber: "gamma-Tubulin redistribution in taxol-treated mitotic cells probed by monoclonal antibodies." dans: Cell motility and the cytoskeleton, Vol. 33, Issue 1, pp. 38-51, (1996) (PubMed).

  • Antigène
    TUBG1 (Tubulin, gamma 1 (TUBG1))
    Autre désignation
    gamma-tubulin (TUBG1 Produits)
    Synonymes
    anticorps GCP-1, anticorps TUBG, anticorps TUBGCP1, anticorps TUBC, anticorps TUBG3, anticorps gamma-tubulin, anticorps Tubg2, anticorps xgam, anticorps 1500010O08Rik, anticorps AI451582, anticorps AI503389, anticorps Tubg, anticorps tubgl, anticorps zgc:55894, anticorps tubulin gamma 1, anticorps gamma-tubulin 1, anticorps gamma-tubulin, anticorps tubulin gamma 1 L homeolog, anticorps Tubulin gamma chain, anticorps tubulin, gamma 1, anticorps tubulin gamma-1 chain, anticorps TUBG1, anticorps tubg1, anticorps tubg1.L, anticorps tbg-1, anticorps Tubg1, anticorps LOC101686824, anticorps LOC101103906
    Sujet
    Tubulin gamma 1,The gamma-tubulin (TUBG1, relative molecular weight about 48 kDa) is a minor member of tubulin family (less that 0.01 % of tubulin dimer). The gamma-tubulin ring structures, however, serve to provide structural primer for initiation of microtubular nucleation and growth, thereby being crutial for microtubule-based cellular processes, above all for mitotic spindle formation. In animal cells, a center of microtubule organization is the centrosome composed of a pair of cylindrical centrioles surrounded by fibrous pericentriolar material containing gamma-tubulin. Formation of the mitotic spindle is preceded by duplication of centrosome during S phase. Before mitosis, both centrosomes increase their microtubule nucleation capacity and form two microtuble asters that are pushed apart from each other by the forces of motor proteins associated at the microtubule surface. Humans possess two gamma-tubulin genes. Gamma-tubulin 1 represents a ubiquitous isotype, whereas gamma-tubulin 2 is found predominantly in the brain, where it may be endowed with divergent functions beyond microtubule nucleation.,TUBG
    ID gène
    7283
    UniProt
    P23258
    Pathways
    Dynamique des Microtubules, M Phase
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