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FAS anticorps (AA 150-250)

FAS Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3020739
  • Antigène Voir toutes FAS Anticorps
    FAS (TNF Receptor Superfamily, Member 6 (FAS))
    Épitope
    • 25
    • 16
    • 16
    • 8
    • 8
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 150-250
    Reactivité
    • 226
    • 68
    • 66
    • 19
    • 9
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 158
    • 102
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Lapin
    Clonalité
    • 155
    • 116
    • 1
    Polyclonal
    Conjugué
    • 130
    • 29
    • 25
    • 12
    • 11
    • 7
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp FAS est non-conjugé
    Application
    • 166
    • 131
    • 75
    • 68
    • 40
    • 36
    • 34
    • 26
    • 26
    • 20
    • 19
    • 12
    • 8
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    EHGIIKECTL TSNTKCKEEG SRSNLGWLCL LLLPIPLIVW VKRKEVQKTC RKHRKENQGS HESPTLNPET VAINLSDVDL SKYITTIAGV MTLSQVKGFV R
     Réactivité croisée
    Humain, Souris, Rat
    Attributs du produit
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogène
    A synthetic peptide corresponding to a sequence within amino acids 150-250 of human Fas (NP_000034.1).
    Isotype
    IgG
  • Indications d'application
    WB,1:500 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid freeze / thaw cycles
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Wang, Yan, Xiao, Zhou, Liu, Zeng, Liu, Li, Yuan, Wu, Yi, Razack, Wen: "Anti-obesity effect of a traditional Chinese dietary habit-blending lard with vegetable oil while cooking." dans: Scientific reports, Vol. 7, Issue 1, pp. 14689, (2017) (PubMed).

    Chen, Gu, Jiang, Zhang: "Nuclear translocation of nuclear factor kappa B is regulated by G protein signaling pathway in arsenite-induced apoptosis in HBE cell line." dans: Environmental toxicology, (2015) (PubMed).

    Gu, Chen, Jiang, Zhang: "Resveratrol Synergistically Triggers Apoptotic Cell Death with Arsenic Trioxide via Oxidative Stress in Human Lung Adenocarcinoma A549 Cells." dans: Biological trace element research, Vol. 163, Issue 1-2, pp. 112-23, (2015) (PubMed).

    Chen, Jiang, Lai, Liu, Zhang: "Resveratrol protects against arsenic trioxide-induced oxidative damage through maintenance of glutathione homeostasis and inhibition of apoptotic progression." dans: Environmental and molecular mutagenesis, (2014) (PubMed).

  • Antigène
    FAS (TNF Receptor Superfamily, Member 6 (FAS))
    Autre désignation
    FAS (FAS Produits)
    Synonymes
    anticorps ALPS1A, anticorps APO-1, anticorps APT1, anticorps CD95, anticorps FAS1, anticorps FASTM, anticorps TNFRSF6, anticorps AI196731, anticorps APO1, anticorps TNFR6, anticorps Tnfrsf6, anticorps lpr, anticorps Fas cell surface death receptor, anticorps Fas (TNF receptor superfamily member 6), anticorps FAS, anticorps Fas, anticorps fas
    Sujet
    The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF-kappaB, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells. Several alternatively spliced transcript variants have been described, some of which are candidates for nonsense-mediated mRNA decay (NMD). The isoforms lacking the transmembrane domain may negatively regulate the apoptosis mediated by the full length isoform.,ALPS1A,APO-1,APT1,CD95,FAS1,FASTM,TNFRSF6,FAS,Cell Biology & Developmental Biology,Apoptosis,Mitochondrial Control of Apoptosis,Inhibition of Apoptosis,Death Receptor Signaling Pathway,Immunology & Inflammation,CD markers,Cytokines,TNF,Cell Intrinsic Innate Immunity Signaling Pathway,Neuroscience,Neurodegenerative Diseases,FAS
    Poids moléculaire
    9 kDa/11 kDa/14 kDa/16 kDa/24 kDa/35 kDa/37 kDa
    ID gène
    355
    UniProt
    P25445
    Pathways
    Signalisation p53, Apoptose, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
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