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THRB anticorps (AA 1-250)

THRB Reactivité: Humain WB, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3022183
  • Antigène Voir toutes THRB Anticorps
    THRB (Thyroid Hormone Receptor, beta (THRB))
    Épitope
    • 16
    • 8
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-250
    Reactivité
    • 52
    • 33
    • 32
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    Humain
    Hôte
    • 50
    • 2
    • 2
    Lapin
    Clonalité
    • 52
    • 2
    Polyclonal
    Conjugué
    • 35
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp THRB est non-conjugé
    Application
    • 50
    • 22
    • 15
    • 13
    • 13
    • 12
    • 7
    • 4
    • 4
    • 4
    • 3
    • 2
    Western Blotting (WB), Immunofluorescence (IF)
    Séquence
    MTPNSMTENG LTAWDKPKHC PDREHDWKLV GMSEACLHRK SHSERRSTLK NEQSSPHLIQ TTWTSSIFHL DHDDVNDQSV SSAQTFQTEE KKCKGYIPSY LDKDELCVVC GDKATGYHYR CITCEGCKGF FRRTIQKNLH PSYSCKYEGK CVIDKVTRNQ CQECRFKKCI YVGMATDLVL DDSKRLAKRK LIEENREKRR REELQKSIGH KPEPTDEEWE LIKTVTEAHV ATNAQGSHWK QKRKFLPEDI
     Réactivité croisée
    Humain, Souris, Rat
    Attributs du produit
    Polyclonal Antibodies
    Immunogène
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human THRB (NP_000452.2).
    Isotype
    IgG
    Top Product
    Discover our top product THRB Anticorps primaire
  • Indications d'application
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid freeze / thaw cycles
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    THRB (Thyroid Hormone Receptor, beta (THRB))
    Autre désignation
    THRB (THRB Produits)
    Synonymes
    anticorps C-ERBA-2, anticorps C-ERBA-BETA, anticorps ERBA2, anticorps GRTH, anticorps NR1A2, anticorps PRTH, anticorps THR1, anticorps THRB1, anticorps THRB2, anticorps Nr1a2, anticorps T3R[b], anticorps T3Rbeta, anticorps Thrb1, anticorps Thrb2, anticorps c-erbAbeta, anticorps TR-beta, anticorps TR[b]1, anticorps fj24f03, anticorps trb, anticorps wu:fj24f03, anticorps CTR BETA 2, anticorps TR-BETA, anticorps LOC734147, anticorps thrb, anticorps THRB, anticorps C-erba-beta, anticorps RATT3REC, anticorps T3rec, anticorps TRbeta, anticorps THR, anticorps TRbeta1, anticorps thyroid hormone receptor beta, anticorps thyroid hormone receptor, beta, anticorps thyroid hormone receptor, beta S homeolog, anticorps thyroid hormone receptor, beta L homeolog, anticorps THRB, anticorps Thrb, anticorps thrb, anticorps thrb.S, anticorps thrb.L
    Sujet
    The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene.,THRB,C-ERBA-2,C-ERBA-BETA,ERBA2,GRTH,NR1A2,PRTH,THR1,THRB1,THRB2,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Endocrine & Metabolism,Neuroscience,THRB
    Poids moléculaire
    52 kDa/54 kDa
    ID gène
    7068
    UniProt
    P10828
    Pathways
    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Sensory Perception of Sound
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