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RASA1 anticorps (AA 140-220)

RASA1 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3022297
  • Antigène Voir toutes RASA1 Anticorps
    RASA1 (RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1))
    Épitope
    • 15
    • 15
    • 13
    • 9
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 140-220
    Reactivité
    • 48
    • 30
    • 29
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 70
    • 8
    • 1
    Lapin
    Clonalité
    • 72
    • 7
    Polyclonal
    Conjugué
    • 31
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp RASA1 est non-conjugé
    Application
    • 36
    • 32
    • 26
    • 26
    • 9
    • 7
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    PPYLPPLGAG LGTVDEGDSL DGPEYEEEEV AIPLTAPPTN QWYHGKLDRT IAEERLRQAG KSGSYLIRES DRRPGSFVLS F
     Réactivité croisée
    Humain, Souris, Rat
    Attributs du produit
    Polyclonal Antibodies
    Immunogène
    Recombinant fusion protein containing a sequence corresponding to amino acids 140-220 of human RASA1 (NP_002881.1).
    Isotype
    IgG
    Top Product
    Discover our top product RASA1 Anticorps primaire
  • Indications d'application
    WB,1:500 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid freeze / thaw cycles
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    RASA1 (RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1))
    Autre désignation
    RASA1 (RASA1 Produits)
    Synonymes
    anticorps CG9209, anticorps D-RasGAP, anticorps Dmel\\CG9209, anticorps RAS-GAP, anticorps RasGAP, anticorps RasGap, anticorps rasGap, anticorps CM-AVM, anticorps CMAVM, anticorps GAP, anticorps PKWS, anticorps RASA, anticorps RASGAP, anticorps p120GAP, anticorps p120RASGAP, anticorps GAPX, anticorps Rasa, anticorps Gap, anticorps vacuolar peduncle, anticorps RAS p21 protein activator 1, anticorps vap, anticorps RASA1, anticorps Rasa1
    Sujet
    The protein encoded by this gene is located in the cytoplasm and is part of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. Mutations leading to changes in the binding sites of either protein are associated with basal cell carcinomas. Mutations also have been associated with hereditary capillary malformations (CM) with or without arteriovenous malformations (AVM) and Parkes Weber syndrome. Alternative splicing results in two isoforms where the shorter isoform, lacking the N-terminal hydrophobic region but retaining the same activity, appears to be abundantly expressed in placental but not adult tissues.,RASA1,CM-AVM,CMAVM,GAP,PKWS,RASA,RASGAP,p120,p120GAP,p120RASGAP,Cancer,Signal Transduction,G protein signaling,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Immunology & Inflammation,B Cell Receptor Signaling Pathway,RASA1
    Poids moléculaire
    58 kDa/100 kDa/101 kDa/116 kDa
    ID gène
    5921
    UniProt
    P20936
    Pathways
    Regulation of Actin Filament Polymerization, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals
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