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ABCG8 anticorps (AA 1-320)

ABCG8 Reactivité: Humain WB, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3022643
  • Antigène Voir toutes ABCG8 Anticorps
    ABCG8 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 8 (ABCG8))
    Épitope
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-320
    Reactivité
    • 21
    • 14
    • 13
    Humain
    Hôte
    • 26
    Lapin
    Clonalité
    • 26
    Polyclonal
    Conjugué
    • 15
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ABCG8 est non-conjugé
    Application
    • 15
    • 11
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Séquence
    MAGKAAEERG LPKGATPQDT SGLQDRLFSS ESDNSLYFTY SGQPNTLEVR DLNYQVDLAS QVPWFEQLAQ FKMPWTSPSC QNSCELGIQN LSFKVRSGQM LAIIGSSGCG RASLLDVITG RGHGGKIKSG QIWINGQPSS PQLVRKCVAH VRQHNQLLPN LTVRETLAFI AQMRLPRTFS QAQRDKRVED VIAELRLRQC ADTRVGNMYV RGLSGGERRR VSIGVQLLWN PGILILDEPT SGLDSFTAHN LVKTLSRLAK GNRLVLISLH QPRSDIFRLF DLVLLMTSGT PIYLGAAQHM VQYFTAIGYP CPRYSNPADF
     Réactivité croisée
    Humain
    Attributs du produit
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogène
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-320 of human ABCG8 (NP_071882.1).
    Isotype
    IgG
  • Indications d'application
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid freeze / thaw cycles
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Chen, Wu: "Role of Baicalin and Liver X Receptor Alpha in the Formation of Cholesterol Gallstones in Mice." dans: Gastroenterology research and practice, Vol. 2020, pp. 1343969, (2020) (PubMed).

  • Antigène
    ABCG8 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 8 (ABCG8))
    Autre désignation
    ABCG8 (ABCG8 Produits)
    Synonymes
    anticorps DDBDRAFT_0167690, anticorps DDBDRAFT_0191232, anticorps DDB_0167690, anticorps DDB_0191232, anticorps zgc:172358, anticorps GBD4, anticorps STSL, anticorps 1300003C16Rik, anticorps AI114946, anticorps sterolin-2, anticorps ATP binding cassette subfamily G member 8, anticorps ATP-binding cassette sub-family G member 8, anticorps ABC transporter G family protein, anticorps ATP-binding cassette, sub-family G (WHITE), member 8, anticorps ABCG8, anticorps PTRG_02054, anticorps abcG8, anticorps abcg8, anticorps Abcg8
    Sujet
    The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions to exclude non-cholesterol sterol entry at the intestinal level, promote excretion of cholesterol and sterols into bile, and to facilitate transport of sterols back into the intestinal lumen. It is expressed in a tissue-specific manner in the liver, intestine, and gallbladder. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG5. Mutations in this gene may contribute to sterol accumulation and atherosclerosis, and have been observed in patients with sitosterolemia.,ABCG8,GBD4,STSL,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Cholesterol Metabolism,Cardiovascular,Heart,Lipids,Cardiovascular diseases,Heart disease,ABCG8
    Poids moléculaire
    75 kDa
    ID gène
    64241
    UniProt
    Q9H221
    Pathways
    Lipid Metabolism
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