XRCC3 anticorps (AA 62-346)

N° du produit ABIN3023006

Détail du produit anti-XRCC3 anticorps

Antigène: XRCC3 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3 (XRCC3))

Épitope: AA 62-346

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp XRCC3 est non-conjugé

Application: Western Blotting (WB)

Séquence: ILTALQLHQQ KERFPTQHQR LSLGCPVLDA LLRGGLPLDG ITELAGRSSA GKTQLALQLC LAVQFPRQHG GLEAGAVYIC TEDAFPHKRL QQLMAQQPRL RTDVPGELLQ KLRFGSQIFI EHVADVDTLL ECVNKKVPVL LSRGMARLVV IDSVAAPFRC EFDSQASAPR ARHLQSLGAT LRELSSAFQS PVLCINQVTE AMEEQGAAHG PLGFWDERVS PALGITWANQ LLVRLLADRL REEEAALGCP ARTLRVLSAP HLPPSSCSYT ISAEGVRGTP GTQSH

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 62-346 of human XRCC3 (NP_001093588.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-XRCC3 (ABIN3023006)

Zhang, Tang, Jiang, Mao: "The transcription factor GATA3 is required for homologous recombination repair by regulating CtIP expression." dans: Oncogene, Vol. 36, Issue 36, pp. 5168-5176, (2017) (PubMed).

Dong, Wang, Wang, Zhang, Zhu, Gao, Yang, Qin, Liang, Chen, Deng, Ning, Liang, Gao, Xu: "A stress-induced cellular aging model with postnatal neural stem cells." dans: Cell death & disease, Vol. 5, pp. e1116, (2014) (PubMed).

Détails sur XRCC3

Antigène: XRCC3 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3 (XRCC3))

Autre désignation: XRCC3 (XRCC3 Produits)

Synonymes: anticorps CMM6, anticorps 4432412E01Rik, anticorps AI182522, anticorps AW537713, anticorps MGC69118, anticorps im:7142103, anticorps zgc:101608, anticorps si:dkey-11b8.1, anticorps xrcc3, anticorps XRCC3, anticorps X-ray repair cross complementing 3, anticorps X-ray repair complementing defective repair in Chinese hamster cells 3, anticorps X-ray repair complementing defective repair in Chinese hamster cells 3 L homeolog, anticorps XRCC3, anticorps Xrcc3, anticorps xrcc3.L, anticorps xrcc3

Sujet: This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identified.,XRCC3,CMM6,Epigenetics & Nuclear Signaling,DNA Damage & Repair,XRCC3

Poids moléculaire: 37 kDa

ID gène: 7517

UniProt: O43542

Pathways: Réparation de l'ADN