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ATF2 anticorps (AA 1-190)

ATF2 Reactivité: Humain WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3023064
  • Antigène Voir toutes ATF2 Anticorps
    ATF2 (Activating Transcription Factor 2 (ATF2))
    Épitope
    • 49
    • 36
    • 26
    • 26
    • 24
    • 24
    • 23
    • 23
    • 15
    • 15
    • 14
    • 14
    • 12
    • 10
    • 9
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-190
    Reactivité
    • 294
    • 229
    • 206
    • 16
    • 12
    • 11
    • 8
    • 7
    • 7
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 326
    • 12
    • 2
    • 1
    Lapin
    Clonalité
    • 312
    • 29
    Polyclonal
    Conjugué
    • 153
    • 20
    • 16
    • 16
    • 16
    • 15
    • 15
    • 15
    • 13
    • 12
    • 9
    • 8
    • 8
    • 8
    • 8
    • 5
    • 4
    Cet anticorp ATF2 est non-conjugé
    Application
    • 240
    • 118
    • 112
    • 111
    • 75
    • 61
    • 59
    • 35
    • 33
    • 22
    • 15
    • 10
    • 6
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    MKFKLHVNSA RQYKDLWNMS DDKPFLCTAP GCGQRFTNED HLAVHKHKHE MTLKFGPARN DSVIVADQTP TPTRFLKNCE EVGLFNELAS PFENEFKKAS EDDIKKMPLD LSPLATPIIR SKIEEPSVVE TTHQDSPLPH PESTTSDEKE VPLAQTAQPT SAIVRPASLQ VPNVLLTSSD SSVIIQQAVP
     Réactivité croisée
    Humain, Souris, Rat
    Attributs du produit
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogène
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human ATF2 (NP_001871.2).
    Isotype
    IgG
  • Indications d'application
    WB,1:500 - 1:2000,IHC,1:50 - 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid freeze / thaw cycles
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Zhang, He, Wang, Zhang, Huang, Xiong, Yan, Wu, Ren, Han, Liu, Qian, Du: "Virus-Triggered ATP Release Limits Viral Replication through Facilitating IFN-β Production in a P2X7-Dependent Manner." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 199, Issue 4, pp. 1372-1381, (2017) (PubMed).

  • Antigène
    ATF2 (Activating Transcription Factor 2 (ATF2))
    Autre désignation
    ATF2 (ATF2 Produits)
    Synonymes
    anticorps CRE-BP1, anticorps CREB2, anticorps HB16, anticorps TREB7, anticorps CG12850, anticorps CG3749, anticorps dATF-2, anticorps DmelCG30420, anticorps CG30420, anticorps CHN1, anticorps Atf-2, anticorps CRE-BP, anticorps Creb2, anticorps D130078H02Rik, anticorps D18875, anticorps Tg(Gzma-Klra1)7Wum, anticorps mXBP, anticorps atf2-A, anticorps atf2l, anticorps activating transcription factor 2, anticorps Activating transcription factor-2, anticorps activating transcription factor 2 S homeolog, anticorps ATF2, anticorps Atf-2, anticorps Atf2, anticorps atf2.S, anticorps atf2
    Sujet
    This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro, thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this gene,CRE-BP1,CREB-2,CREB2,HB16,TREB7,ATF2,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,MAPK-JNK Signaling Pathway,MAPK-P38 Signaling Pathway,Immunology & Inflammation,B Cell Receptor Signaling Pathway,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling,ATF2
    Poids moléculaire
    13- 15 kDa/23-24 kDa/35-54 kDa
    ID gène
    1386
    UniProt
    P15336
    Pathways
    Signalisation MAPK, Signalisation RTK, Thyroid Hormone Synthesis, Activation of Innate immune Response, Chromatin Binding, Myometrial Relaxation and Contraction, Synaptic Membrane, Tube Formation, Toll-Like Receptors Cascades
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