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Histone 3 anticorps (H3K9me2)

H3 Reactivité: Humain WB, IHC, IF, ChIP, IP, ChIP-seq Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3023261
  • Antigène Voir toutes Histone 3 (H3) Anticorps
    Histone 3 (H3)
    Épitope
    • 64
    • 47
    • 46
    • 45
    • 42
    • 37
    • 36
    • 35
    • 35
    • 35
    • 34
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    • 31
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    • 12
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    • 11
    • 10
    • 10
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    • 9
    • 9
    • 8
    H3K9me2
    Reactivité
    • 1411
    • 942
    • 862
    • 59
    • 42
    • 41
    • 41
    • 40
    • 39
    • 35
    • 35
    • 30
    • 30
    • 22
    • 19
    • 6
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 1220
    • 248
    • 12
    • 4
    Lapin
    Clonalité
    • 1121
    • 362
    • 1
    Polyclonal
    Conjugué
    • 827
    • 81
    • 65
    • 64
    • 63
    • 63
    • 63
    • 62
    • 37
    • 33
    • 24
    • 17
    • 17
    • 17
    • 17
    • 17
    • 14
    • 2
    • 1
    Cet anticorp Histone 3 est non-conjugé
    Application
    • 1062
    • 411
    • 382
    • 316
    • 254
    • 188
    • 186
    • 180
    • 163
    • 161
    • 142
    • 127
    • 119
    • 48
    • 38
    • 34
    • 32
    • 20
    • 16
    • 14
    • 7
    • 7
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Chromatin Immunoprecipitation (ChIP), Immunoprecipitation (IP), ChIP DNA-Sequencing (ChIP-seq)
     Réactivité croisée
    Humain, Souris, Rat
    Attributs du produit
    Methylated Antibodies
    Purification
    Affinity purification
    Immunogène
    A synthetic methylated peptide corresponding to residues surrounding K9 of human histone H3
    Isotype
    IgG
    Top Product
    Discover our top product H3 Anticorps primaire
  • Indications d'application
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:200,ChIP,1:50 - 1:200,ChIP-seq,1:50 - 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid freeze / thaw cycles
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Zuo, Rong, Li, Lv, Lan, Tong: "The histone methyltransferase SETD2 is required for expression of acrosin-binding protein 1 and protamines and essential for spermiogenesis in mice." dans: The Journal of biological chemistry, Vol. 293, Issue 24, pp. 9188-9197, (2019) (PubMed).

    Vaughan, Dickson, Whelihan, Johnstone, Cornett, Cheek, Ausherman, Cowles, Sun, Rothbart: "Chromatin structure and its chemical modifications regulate the ubiquitin ligase substrate selectivity of UHRF1." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, Issue 35, pp. 8775-8780, (2018) (PubMed).

    Cao, Liu, Yue, Liu, Pei, Gu, Wang, Jia: "Iron chelation inhibits cancer cell growth and modulates global histone methylation status in colorectal cancer." dans: Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, Vol. 31, Issue 5, pp. 797-805, (2018) (PubMed).

    Zhao, Lei, Zhang, Zheng, Wang, Zhao, Li, Ye, Li, Wei, Wu: "Global histone modification profiling reveals the epigenomic dynamics during malignant transformation in a four-stage breast cancer model." dans: Clinical epigenetics, Vol. 8, pp. 34, (2016) (PubMed).

  • Antigène
    Histone 3 (H3)
    Autre désignation
    Histone H3 (H3 Produits)
    Synonymes
    anticorps H-3, anticorps histocompatibility 3, anticorps H3
    Sujet
    Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.,H3.4,H3/g,H3FT,H3t,HIST3H3,Histone H3,HIST1H3A,Signal Transduction,MAPK-Erk Signaling Pathway,MAPK-P38 Signaling Pathway,Epigenetics & Nuclear Signaling,Epigenetic Modifications,Methylation,Histone H3
    Poids moléculaire
    15 kDa
    ID gène
    8290
    UniProt
    Q16695
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