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LCP2 anticorps (AA 284-533)

LCP2 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3023382
  • Antigène Voir toutes LCP2 Anticorps
    LCP2 (Lymphocyte Cytosolic Protein 2 (SH2 Domain Containing Leukocyte Protein of 76kDa) (LCP2))
    Épitope
    • 20
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 284-533
    Reactivité
    • 61
    • 31
    • 14
    • 3
    Humain
    Hôte
    • 46
    • 16
    • 1
    Lapin
    Clonalité
    • 42
    • 21
    Polyclonal
    Conjugué
    • 39
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Cet anticorp LCP2 est non-conjugé
    Application
    • 34
    • 12
    • 11
    • 8
    • 7
    • 6
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Séquence
    KPPLPPTTER HERSSPLPGK KPPVPKHGWG PDRRENDEDD VHQRPLPQPA LLPMSSNTFP SRSTKPSPMN PLPSSHMPGA FSESNSSFPQ SASLPPYFSQ GPSNRPPIRA EGRNFPLPLP NKPRPPSPAE EENSLNEEWY VSYITRPEAE AALRKINQDG TFLVRDSSKK TTTNPYVLMV LYKDKVYNIQ IRYQKESQVY LLGTGLRGKE DFLSVSDIID YFRKMPLLLI DGKNRGSRYQ CTLTHAAGYP
     Réactivité croisée
    Humain, Souris
    Attributs du produit
    Polyclonal Antibodies
    Immunogène
    Recombinant fusion protein containing a sequence corresponding to amino acids 284-533 of human LCP2 (NP_005556.1).
    Isotype
    IgG
    Top Product
    Discover our top product LCP2 Anticorps primaire
  • Indications d'application
    WB,1:500 - 1:2000
    Restrictions
    For Research Use only
  • Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    LCP2 (Lymphocyte Cytosolic Protein 2 (SH2 Domain Containing Leukocyte Protein of 76kDa) (LCP2))
    Autre désignation
    LCP2 (LCP2 Produits)
    Synonymes
    anticorps AI323664, anticorps BB161688, anticorps SLP-76, anticorps SLP76, anticorps twm, anticorps Slp76, anticorps lymphocyte cytosolic protein 2, anticorps Lcp2, anticorps LCP2
    Sujet
    SLP-76 was originally identified as a substrate of the ZAP-70 protein tyrosine kinase following T cell receptor (TCR) ligation in the leukemic T cell line Jurkat. The SLP-76 locus has been localized to human chromosome 5q33 and the gene structure has been partially characterized in mice. The human and murine cDNAs both encode 533 amino acid proteins that are 72 % identical and comprised of three modular domains. The NH2-terminus contains an acidic region that includes a PEST domain and several tyrosine residues which are phosphorylated following TCR ligation. SLP-76 also contains a central proline-rich domain and a COOH-terminal SH2 domain. A number of additional proteins have been identified that associate with SLP-76 both constitutively and inducibly following receptor ligation, supporting the notion that SLP-76 functions as an adaptor or scaffold protein. Studies using SLP-76 deficient T cell lines or mice have provided strong evidence that SLP-76 plays a positive role in promoting T cell development and activation as well as mast cell and platelet function.,LCP2,SLP-76,SLP76,Signal Transduction,Immunology & Inflammation,T Cell Receptor Signaling Pathway,LCP2
    Poids moléculaire
    60 kDa
    ID gène
    3937
    UniProt
    Q13094
    Pathways
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway
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