anticorps trbp, anticorps trbp1, anticorps trbp2, anticorps MGC97783, anticorps TARBP2, anticorps LOQS, anticorps TRBP, anticorps TRBP1, anticorps TRBP2, anticorps fj51e12, anticorps wu:fj51e12, anticorps zgc:63778, anticorps Prbp, anticorps TAR (HIV-1) RNA binding protein 2, anticorps TARBP2, RISC loading complex RNA binding subunit, anticorps TAR (HIV-1) RNA binding protein 2 L homeolog, anticorps TAR (HIV) RNA binding protein 2, anticorps tarbp2, anticorps TARBP2, anticorps tarbp2.L, anticorps Tarbp2
Sujet
TARBP2 (TAR (HIV-1) RNA binding protein 2) , along with Dicer and Argonaute-2, is part of the RISC (RNA induced silencing complex). As part of the RISC, TRBP2 is important in viral defense. Dicer cleaves dsRNA into siRNA. Through TRBP2-Dicer interaction, the siRNA template is loaded onto Argonaute-2, which cleaves encountered viral mRNA strands complementary to the loaded siRNA base-pair sequence.